International audienceObjectivesThe objectives of this study were to identify actionable genomic alterations in the gynaecological subpopulation of the ProfiLER programme and to report clinical efficacy of recommended targeted treatment (RTT). MethodsThe ProfiLER programme (NCT01774409) is a multicentric prospective trial aiming to implement molecular profiling in patients with advanced refractory cancers. In this programme, tumour DNA is analysed by targeted next-generation sequencing (69 genes) and by whole genome array comparative genomic hybridisation. Clinical cases and genomic profiles are presented in a dedicated molecular tumour board to guide treatment strategies. We report here an analysis of patients with gynaecological cancers i...
© 2015 Olga KondrashovaOvarian cancer is a complex disease composed of multiple distinct molecular a...
BACKGROUND: Metastatic breast cancer remains incurable. Next-generation sequencing (NGS) offers the ...
Abstract Background The clinical utility of molecular...
International audienceObjectivesThe objectives of this study were to identify actionable genomic alt...
International audienceObjectivesThe objectives of this study were to identify actionable genomic alt...
International audienceObjectivesThe objectives of this study were to identify actionable genomic alt...
International audienceObjectivesThe objectives of this study were to identify actionable genomic alt...
International audienceObjectivesThe objectives of this study were to identify actionable genomic alt...
International audienceObjectivesThe objectives of this study were to identify actionable genomic alt...
International audienceLBA100 Background: ProfiLER (NCT01774409) is a molecular profiling clinical tr...
Abstract Previous precision medicine studies have investigated conventional molecular techniques and...
Abstract Background With the growing understanding of the molecular and genetic profiles of cancers,...
AbstractObjectiveTo determine the feasibility and clinical utility of using comprehensive genomic pr...
Molecular features of gynecologic cancers have been investigated in comprehensive studies, but corre...
Abstract Background The clinical utility of molecular profiling of tumor tissue to guide treatment o...
© 2015 Olga KondrashovaOvarian cancer is a complex disease composed of multiple distinct molecular a...
BACKGROUND: Metastatic breast cancer remains incurable. Next-generation sequencing (NGS) offers the ...
Abstract Background The clinical utility of molecular...
International audienceObjectivesThe objectives of this study were to identify actionable genomic alt...
International audienceObjectivesThe objectives of this study were to identify actionable genomic alt...
International audienceObjectivesThe objectives of this study were to identify actionable genomic alt...
International audienceObjectivesThe objectives of this study were to identify actionable genomic alt...
International audienceObjectivesThe objectives of this study were to identify actionable genomic alt...
International audienceObjectivesThe objectives of this study were to identify actionable genomic alt...
International audienceLBA100 Background: ProfiLER (NCT01774409) is a molecular profiling clinical tr...
Abstract Previous precision medicine studies have investigated conventional molecular techniques and...
Abstract Background With the growing understanding of the molecular and genetic profiles of cancers,...
AbstractObjectiveTo determine the feasibility and clinical utility of using comprehensive genomic pr...
Molecular features of gynecologic cancers have been investigated in comprehensive studies, but corre...
Abstract Background The clinical utility of molecular profiling of tumor tissue to guide treatment o...
© 2015 Olga KondrashovaOvarian cancer is a complex disease composed of multiple distinct molecular a...
BACKGROUND: Metastatic breast cancer remains incurable. Next-generation sequencing (NGS) offers the ...
Abstract Background The clinical utility of molecular...