Does genetic variation in the Δ6-desaturase promoter modify the association between α-linolenic acid and the prevalence of metabolic syndrome?
- Truong, Hong
- DiBello, Julia R.
- Ruiz Narváez, Edward A.
- Kraft, Peter
- Campos Núñez, Hannia
- Baylin, Ana
Publication date
January 2009
DOI Publisher
American Society for Nutrition Journal
American Journal of Clinical NutritionAbstract
Background: Eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA) are associated with protection against components of the metabolic syndrome, but the role of α-linolenic acid (ALA), the metabolic precursor of EPA and DHA, has not been studied. The Δ6-desaturase enzyme converts ALA into EPA and DHA, and genetic variation in the Δ6-desaturase gene (FADS2) may affect this conversion.UCR::Vicerrectoría de Investigación::Unidades de Investigación::Ciencias Sociales::Centro Centroamericano de Población (CCP
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