The importance of ions in life sciences can not be overstated. The interaction betweenmetal ions and proteins is vital because it is involved in a variety of biological processes.The ions contribute to stability and function of proteins. Moreover, they are relevant indisease progression.Realistic computer simulations pave the way for drug development, through providingdetailed insights into the dynamics of proteins and various biological processes thatoccur in the body. Such information can be impossible to achieve through experimentsof living subjects in vivo or from test tube experiments in vitro alone. However,theoretical methods have to result in accurate predictions. In my thesis, I studieddifferent ways to handle the ions in simulatio...
Nowadays, computers play an indispensable role in the determination of metal-ligand formation consta...
<p>About one-third of the existing proteins require metal ions as cofactors for their catalytic acti...
Metal ions exist in almost half of the proteins in the protein databank, and they serve as structura...
Ions are ubiquitous in biological systems. Metal ions contribute to biological function as counter i...
AbstractIons in water are important throughout biology, from molecules to organs. Classically, ions ...
This thesis describes an investigation, by computer simulation, into the nature of the metal ion bin...
Proteins interact with ions in various ways. The surface of proteins has an innate capability to bin...
Title: Ion-Protein Interactions Author: Mgr. et Mgr. Jan Heyda Department: Physical and Macromolecul...
Proteins interact with ions in various ways. The surface of proteins has an innate capability to bin...
Title: Ion-Protein Interactions Author: Mgr. et Mgr. Jan Heyda Department: Physical and Macromolecul...
Title: Ion-Protein Interactions Author: Mgr. et Mgr. Jan Heyda Department: Physical and Macromolecul...
AbstractThe solution and complexation chemistry of zinc ions is the basis for zinc biology. In livin...
In this thesis, a series of molecular dynamics simulations have been performed in order to explore s...
Approximately two-thirds of the elements in the periodic table can be cate-gorized as metals. Beside...
abstract: Due to analytical limitations, thermodynamic modeling is a lucrative alternative for obtai...
Nowadays, computers play an indispensable role in the determination of metal-ligand formation consta...
<p>About one-third of the existing proteins require metal ions as cofactors for their catalytic acti...
Metal ions exist in almost half of the proteins in the protein databank, and they serve as structura...
Ions are ubiquitous in biological systems. Metal ions contribute to biological function as counter i...
AbstractIons in water are important throughout biology, from molecules to organs. Classically, ions ...
This thesis describes an investigation, by computer simulation, into the nature of the metal ion bin...
Proteins interact with ions in various ways. The surface of proteins has an innate capability to bin...
Title: Ion-Protein Interactions Author: Mgr. et Mgr. Jan Heyda Department: Physical and Macromolecul...
Proteins interact with ions in various ways. The surface of proteins has an innate capability to bin...
Title: Ion-Protein Interactions Author: Mgr. et Mgr. Jan Heyda Department: Physical and Macromolecul...
Title: Ion-Protein Interactions Author: Mgr. et Mgr. Jan Heyda Department: Physical and Macromolecul...
AbstractThe solution and complexation chemistry of zinc ions is the basis for zinc biology. In livin...
In this thesis, a series of molecular dynamics simulations have been performed in order to explore s...
Approximately two-thirds of the elements in the periodic table can be cate-gorized as metals. Beside...
abstract: Due to analytical limitations, thermodynamic modeling is a lucrative alternative for obtai...
Nowadays, computers play an indispensable role in the determination of metal-ligand formation consta...
<p>About one-third of the existing proteins require metal ions as cofactors for their catalytic acti...
Metal ions exist in almost half of the proteins in the protein databank, and they serve as structura...