Protein kinase A inhibitor, H89, enhances survival and clonogenicity of dissociated human embryonic stem cells through Rho-associated coiled-coil containing protein kinase (ROCK) inhibition

Inhibition of ROCK improves survival of human embryonic stem cell-derived cardiomyocytes after dissociation

Braam, S.R.
Nauw, R.
Ward-van Oostwaard, D.
Mummery, C.
Passier, R.
Beyar, R.
Landesberg, A.

February 2010

In recent years the differentiation efficiency of human embryonic stem cells (hESCs) to cardiomyocyt...

The Rho-associated kinase inhibitor fasudil can replace Y-27632 for use in human pluripotent stem cell research.

Seongjun So
Yeonmi Lee
Jiwan Choi
Seoon Kang
Ji-Yoon Lee
Julie Hwang
Joosung Shin
James R Dutton
Eul-Ju Seo
Beom Hee Lee
Chong Jai Kim
Shoukhrat Mitalipov
Soo Jin Oh
Eunju Kang

January 2020

Poor survival of human pluripotent stem cells (hPSCs) following freezing, thawing, or passaging hind...

Human embryonic and induced pluripotent stem cells maintain phenotype but alter their metabolism after exposure to ROCK inhibitor

Vernardis, SE
Terzoudis, K
Panoskaltsis, N
Mantalaris, A

January 2017

Human pluripotent stem cells (hPSCs) are adhesion-dependent cells that require cultivation in coloni...

Protein kinase A inhibitor, H89, significantly enhances survival rate of dissociated human embryonic stem cells following cryopreservation

Zhang, Liang
Xu, Yanqing
Xu, Jiandong
Wei, Yuping
Xu, Xia

October 2016

ObjectivesHuman embryonic stem cells (hESCs) have huge potential for establishment of disease mode...

Identification and characterization of regulators of survival in human pluripotent stem cells

Sherman, Sean Patrick

January 2012

Human pluripotent stem cells (hPSCs) can be derived from the inner cell mass of a developing blastoc...

Enhancement of cell recovery for dissociated human embryonic stem cells after cryopreservation

Xu, Xia
Cowley, Sally
Flaim, Christopher
James, William
Seymour, Lenard W
Cui, Zhanfeng

May 2010

Due to widespread applications of human embryonic stem (hES) cells, it is essential to establish eff...

RESEARCH ARTICLE ROCK Inhibition Facilitates In Vitro

Expansion Glioblastoma
Stem-like Cells
Samantha G. Tilson
Elizabeth M. Haley
Ursula L. Triantafillu
David A. Dozier
Catherine P. Langford
G. Yancey Gillespie
Yonghyun Kim

August 2016

Due to their stem-like characteristics and their resistance to existing chemo- and radiation therapi...

Characterisation of a novel pluripotent stem cell survival compound

Cowan, Scott

January 2013

Human pluripotent stem cells (hPSC) such as human embryonic stem cells (hESC) and induced pluripoten...

Treatment of human embryos with the TGFβ inhibitor SB431542 increases epiblast proliferation and permits successful human embryonic stem cell derivation

Van der Jeught, Margot
Heindryckx, Björn
O'Leary, Thomas
Duggal, Galbha
Ghimire, Sabitri
Lierman, Sylvie
Van Roy, Nadine
Chuva de Sousa Lopes, Susana Marina
Deroo, Tom
Deforce, Dieter
De Sutter, Petra

January 2014

Study question: Is there an effect of the TGFb inhibitor SB431542 (SB) on the epiblast compartment o...

Effect of Rho–Associated Kinase Inhibitor on Growth Behaviors of Human Induced Pluripotent Stem Cells in Suspension Culture

Takaki Matsumoto
Mee-Hae Kim
Masahiro Kino-oka

October 2022

Rho–associated protein kinase (ROCK) inhibitors are used for the survival of single-dissociated huma...

The ROCK inhibitor Y-27632 improves recovery of human embryonic stem cells after fluorescence-activated cell sorting with multiple cell surface markers.

Nil Emre
Jason G Vidal
Jeanne Elia
Eric D O'Connor
Rosanto I Paramban
Michael P Hefferan
Roman Navarro
Danielle S Goldberg
Nissi M Varki
Martin Marsala
Christian T Carson

BACKGROUND: Due to the inherent sensitivity of human embryonic stem cells (hESCs) to manipulations, ...

ROCK Inhibition Extends Passage of Pluripotent Stem Cell‐Derived Retinal Pigmented Epithelium

Croze, Roxanne H
Buchholz, David E
Radeke, Monte J
Thi, William J
Hu, Qirui
Coffey, Peter J
Clegg, Dennis O

September 2014

Human embryonic stem cells (hESCs) offer a potentially unlimited supply of cells for emerging cell-b...

Novel regulators of stem cell fates identified by a multivariate phenotype screen of small compounds on human embryonic stem cell colonies

Barbaric, Ivana
Gokhale, Paul J.
Jones, Mark
Glen, Adam
Baker, Duncan
Andrews, Peter W.

January 2010

Understanding the complex mechanisms that govern the fate decisions of human embryonic stem cells (h...

RESEARCH ARTICLE Rho-Associated Kinase Inhibitor (Y-27632) Attenuates Doxorubicin-Induced Apoptosis of Human Cardiac Stem Cells

Lijuan Kan
Aubrie Smith
Miao Chen
Benjamin T. Ledford
Huimin Fan
Zhongmin Liu Jia-qiang

August 2016

Background Recent clinical trials using c-kit+ human cardiac stem cells (CSCs) demonstrated promisin...

Selective Elimination of Culture-Adapted Human Embryonic Stem Cells with BH3 Mimetics

Seung-Ju Cho
Keun-Tae Kim
Ho-Chang Jeong
Ju-Chan Park
Ok-Seon Kwon
Yun-Ho Song
Joong-Gon Shin
Seungmin Kang
Wankyu Kim
Hyoung Doo Shin
Mi-Ok Lee
Sung-Hwan Moon
Hyuk-Jin Cha

November 2018

Summary: The selective survival advantage of culture-adapted human embryonic stem cells (hESCs) is a...

Inhibition of ROCK improves survival of human embryonic stem cell-derived cardiomyocytes after dissociation

Braam, S.R.
Nauw, R.
Ward-van Oostwaard, D.
Mummery, C.
Passier, R.
Beyar, R.
Landesberg, A.

February 2010

In recent years the differentiation efficiency of human embryonic stem cells (hESCs) to cardiomyocyt...

The Rho-associated kinase inhibitor fasudil can replace Y-27632 for use in human pluripotent stem cell research.

Seongjun So
Yeonmi Lee
Jiwan Choi
Seoon Kang
Ji-Yoon Lee
Julie Hwang
Joosung Shin
James R Dutton
Eul-Ju Seo
Beom Hee Lee
Chong Jai Kim
Shoukhrat Mitalipov
Soo Jin Oh
Eunju Kang

January 2020

Poor survival of human pluripotent stem cells (hPSCs) following freezing, thawing, or passaging hind...

Human embryonic and induced pluripotent stem cells maintain phenotype but alter their metabolism after exposure to ROCK inhibitor

Vernardis, SE
Terzoudis, K
Panoskaltsis, N
Mantalaris, A

January 2017

Human pluripotent stem cells (hPSCs) are adhesion-dependent cells that require cultivation in coloni...

Protein kinase A inhibitor, H89, significantly enhances survival rate of dissociated human embryonic stem cells following cryopreservation

Zhang, Liang
Xu, Yanqing
Xu, Jiandong
Wei, Yuping
Xu, Xia

October 2016

ObjectivesHuman embryonic stem cells (hESCs) have huge potential for establishment of disease mode...

Identification and characterization of regulators of survival in human pluripotent stem cells

Sherman, Sean Patrick

January 2012

Human pluripotent stem cells (hPSCs) can be derived from the inner cell mass of a developing blastoc...

Enhancement of cell recovery for dissociated human embryonic stem cells after cryopreservation

Xu, Xia
Cowley, Sally
Flaim, Christopher
James, William
Seymour, Lenard W
Cui, Zhanfeng

May 2010

Due to widespread applications of human embryonic stem (hES) cells, it is essential to establish eff...

RESEARCH ARTICLE ROCK Inhibition Facilitates In Vitro

Expansion Glioblastoma
Stem-like Cells
Samantha G. Tilson
Elizabeth M. Haley
Ursula L. Triantafillu
David A. Dozier
Catherine P. Langford
G. Yancey Gillespie
Yonghyun Kim

August 2016

Due to their stem-like characteristics and their resistance to existing chemo- and radiation therapi...

Characterisation of a novel pluripotent stem cell survival compound

Cowan, Scott

January 2013

Human pluripotent stem cells (hPSC) such as human embryonic stem cells (hESC) and induced pluripoten...

Treatment of human embryos with the TGFβ inhibitor SB431542 increases epiblast proliferation and permits successful human embryonic stem cell derivation

Van der Jeught, Margot
Heindryckx, Björn
O'Leary, Thomas
Duggal, Galbha
Ghimire, Sabitri
Lierman, Sylvie
Van Roy, Nadine
Chuva de Sousa Lopes, Susana Marina
Deroo, Tom
Deforce, Dieter
De Sutter, Petra

January 2014

Study question: Is there an effect of the TGFb inhibitor SB431542 (SB) on the epiblast compartment o...

Effect of Rho–Associated Kinase Inhibitor on Growth Behaviors of Human Induced Pluripotent Stem Cells in Suspension Culture

Takaki Matsumoto
Mee-Hae Kim
Masahiro Kino-oka

October 2022

Rho–associated protein kinase (ROCK) inhibitors are used for the survival of single-dissociated huma...

The ROCK inhibitor Y-27632 improves recovery of human embryonic stem cells after fluorescence-activated cell sorting with multiple cell surface markers.

Nil Emre
Jason G Vidal
Jeanne Elia
Eric D O'Connor
Rosanto I Paramban
Michael P Hefferan
Roman Navarro
Danielle S Goldberg
Nissi M Varki
Martin Marsala
Christian T Carson

BACKGROUND: Due to the inherent sensitivity of human embryonic stem cells (hESCs) to manipulations, ...

ROCK Inhibition Extends Passage of Pluripotent Stem Cell‐Derived Retinal Pigmented Epithelium

Croze, Roxanne H
Buchholz, David E
Radeke, Monte J
Thi, William J
Hu, Qirui
Coffey, Peter J
Clegg, Dennis O

September 2014

Human embryonic stem cells (hESCs) offer a potentially unlimited supply of cells for emerging cell-b...

Novel regulators of stem cell fates identified by a multivariate phenotype screen of small compounds on human embryonic stem cell colonies

Barbaric, Ivana
Gokhale, Paul J.
Jones, Mark
Glen, Adam
Baker, Duncan
Andrews, Peter W.

January 2010

Understanding the complex mechanisms that govern the fate decisions of human embryonic stem cells (h...

RESEARCH ARTICLE Rho-Associated Kinase Inhibitor (Y-27632) Attenuates Doxorubicin-Induced Apoptosis of Human Cardiac Stem Cells

Lijuan Kan
Aubrie Smith
Miao Chen
Benjamin T. Ledford
Huimin Fan
Zhongmin Liu Jia-qiang

August 2016

Background Recent clinical trials using c-kit+ human cardiac stem cells (CSCs) demonstrated promisin...

Selective Elimination of Culture-Adapted Human Embryonic Stem Cells with BH3 Mimetics

Seung-Ju Cho
Keun-Tae Kim
Ho-Chang Jeong
Ju-Chan Park
Ok-Seon Kwon
Yun-Ho Song
Joong-Gon Shin
Seungmin Kang
Wankyu Kim
Hyoung Doo Shin
Mi-Ok Lee
Sung-Hwan Moon
Hyuk-Jin Cha

November 2018

Summary: The selective survival advantage of culture-adapted human embryonic stem cells (hESCs) is a...

Inhibition of ROCK improves survival of human embryonic stem cell-derived cardiomyocytes after dissociation

Braam, S.R.
Nauw, R.
Ward-van Oostwaard, D.
Mummery, C.
Passier, R.
Beyar, R.
Landesberg, A.

February 2010

In recent years the differentiation efficiency of human embryonic stem cells (hESCs) to cardiomyocyt...

The Rho-associated kinase inhibitor fasudil can replace Y-27632 for use in human pluripotent stem cell research.

Seongjun So
Yeonmi Lee
Jiwan Choi
Seoon Kang
Ji-Yoon Lee
Julie Hwang
Joosung Shin
James R Dutton
Eul-Ju Seo
Beom Hee Lee
Chong Jai Kim
Shoukhrat Mitalipov
Soo Jin Oh
Eunju Kang

January 2020

Poor survival of human pluripotent stem cells (hPSCs) following freezing, thawing, or passaging hind...

Human embryonic and induced pluripotent stem cells maintain phenotype but alter their metabolism after exposure to ROCK inhibitor

Vernardis, SE
Terzoudis, K
Panoskaltsis, N
Mantalaris, A

January 2017

Human pluripotent stem cells (hPSCs) are adhesion-dependent cells that require cultivation in coloni...

Protein kinase A inhibitor, H89, enhances survival and clonogenicity of dissociated human embryonic stem cells through Rho-associated coiled-coil containing protein kinase (ROCK) inhibition

Abstract

Extracted data

Protein kinase A inhibitor, H89, enhances survival and clonogenicity of dissociated human embryonic stem cells through Rho-associated coiled-coil containing protein kinase (ROCK) inhibition

Abstract

Extracted data

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