A major goal of synthetic biology is to develop a deeper understanding of biological design principles from the bottom up, by building circuits and studying their behavior in cells. Investigators initially sought to design circuits "from scratch" that functioned as independently as possible from the underlying cellular system. More recently, researchers have begun to develop a new generation of synthetic circuits that integrate more closely with endogenous cellular processes. These approaches are providing fundamental insights into the regulatory architecture, dynamics, and evolution of genetic circuits and enabling new levels of control across diverse biological systems
A mechanistic understanding of living cells and the complex interplay between their biochemical and ...
Advances in synthetic biology are contributing to diverse research areas, from basic biology to bi...
The concept of reengineering and rewiring of pathways and gene regulatory networks for novel uses, a...
Synthetic circuits offer great promise for generating insights into nature's underlying design princ...
Gene regulatory networks lay at the foundation of biological function and are responsible for drivin...
Engineering synthetic gene regulatory circuits proceeds through iterative cycles of design, building...
Like life itself, synthetic biology began with unicellular organisms. Early synthetic biologists bu...
Synthetic biology has exploited genetic engineering technology and systems theory to decipher the na...
AbstractThe ongoing merge between engineering and biology has contributed to the emerging field of s...
Living organisms are differentiated by their genetic material-millions to billions of DNA bases enco...
Motivation: In principle, novel genetic circuits can be engineered using standard parts with well-un...
The development and progress in synthetic biologyhas been remarkable. Although still in its infancy,...
Cells navigate environments, communicate and build complex patterns by initiating gene expression in...
Living cells are exquisite systems. They are strongly regulated to perform in highly specific ways, ...
Synthetic biology aims to make the engineering of biology faster and more predictable. In contrast, ...
A mechanistic understanding of living cells and the complex interplay between their biochemical and ...
Advances in synthetic biology are contributing to diverse research areas, from basic biology to bi...
The concept of reengineering and rewiring of pathways and gene regulatory networks for novel uses, a...
Synthetic circuits offer great promise for generating insights into nature's underlying design princ...
Gene regulatory networks lay at the foundation of biological function and are responsible for drivin...
Engineering synthetic gene regulatory circuits proceeds through iterative cycles of design, building...
Like life itself, synthetic biology began with unicellular organisms. Early synthetic biologists bu...
Synthetic biology has exploited genetic engineering technology and systems theory to decipher the na...
AbstractThe ongoing merge between engineering and biology has contributed to the emerging field of s...
Living organisms are differentiated by their genetic material-millions to billions of DNA bases enco...
Motivation: In principle, novel genetic circuits can be engineered using standard parts with well-un...
The development and progress in synthetic biologyhas been remarkable. Although still in its infancy,...
Cells navigate environments, communicate and build complex patterns by initiating gene expression in...
Living cells are exquisite systems. They are strongly regulated to perform in highly specific ways, ...
Synthetic biology aims to make the engineering of biology faster and more predictable. In contrast, ...
A mechanistic understanding of living cells and the complex interplay between their biochemical and ...
Advances in synthetic biology are contributing to diverse research areas, from basic biology to bi...
The concept of reengineering and rewiring of pathways and gene regulatory networks for novel uses, a...