Chem. Eng. Sci.

Particles have been investigated intensively in recent years. However, the broad size distribution of particles limited their application in biomedical field and also brought difficulty in studying the effect of particle properties. It is necessary to develop techniques which could be utilized to fabricate uniform sized and size controllable particles. Membrane emulsification technique is one of them which have been reported frequently for preparing various particles with narrow size distribution. Our research group carried out much work on the utilization of membrane emulsification technique in preparing particles for biomedical application. In this review, these studies were introduced in brief. The effect of particle properties on their application mainly as drug delivery system and vaccine adjuvant would also be introduced. (C) 2014 Elsevier Ltd. All rights reserved.Particles have been investigated intensively in recent years. However, the broad size distribution of particles limited their application in biomedical field and also brought difficulty in studying the effect of particle properties. It is necessary to develop techniques which could be utilized to fabricate uniform sized and size controllable particles. Membrane emulsification technique is one of them which have been reported frequently for preparing various particles with narrow size distribution. Our research group carried out much work on the utilization of membrane emulsification technique in preparing particles for biomedical application. In this review, these studies were introduced in brief. The effect of particle properties on their application mainly as drug delivery system and vaccine adjuvant would also be introduced. (C) 2014 Elsevier Ltd. All rights reserved