Biotechnol. Lett.

Rice chaff was used as the substrate for the production of fibrinolytic enzyme by Fusarium oxysporum in solid state fermentation. The optimized moisture content of the medium was 30 - 50% (v/w). An inoculum of 5 - 10% (v/v) and an average particle size of 400 mu m for the substrate were optimum for productivity and enzyme activity of 80 IU per mi filtrate was achieved after 96 hours of fermentation.Rice chaff was used as the substrate for the production of fibrinolytic enzyme by Fusarium oxysporum in solid state fermentation. The optimized moisture content of the medium was 30 - 50% (v/w). An inoculum of 5 - 10% (v/v) and an average particle size of 400 mu m for the substrate were optimum for productivity and enzyme activity of 80 IU per mi filtrate was achieved after 96 hours of fermentation