Simultaneous determination of irinotecan (CPT-11) and SN-38 in tissue culture media and cancer cells by high performance liquid chromatography: Application to cellular metabolism and accumulation studies

Simultaneous Determination of the Lactone and Carboxylate Forms of Irinotecan (CPT-11) and its Active Metabolite SN-38 by High-Performance Liquid Chromatography: Application to Plasma Pharmacokinetic Studies in the Rat

Yang, Xiaoxia
Hu, Zeping
Chan, Sui Yung
Goh, Boon Cher
Duan, Wei
Chan, Eli
Zhou, Shufeng

July 2005

Irinotecan (CPT-11) and its main metabolite SN-38 are potent anticancer derivatives of camptothecin ...

Simultaneous Determination of the Lactone and Carboxylate Forms of Irinotecan (CPT-11) and its Active Metabolite SN-38 by High-Performance Liquid Chromatography: Application to Plasma Pharmacokinetic Studies in the Rat

Yang, Xiaoxia
Hu, Zeping
Chan, Sui Yung
Goh, Boon Cher
Duan, Wei
Chan, Eli
Zhou, Shufeng

July 2005

Irinotecan (CPT-11) and its main metabolite SN-38 are potent anticancer derivatives of camptothecin ...

Simultaneous Determination of the Lactone and Carboxylate Forms of Irinotecan (CPT-11) and its Active Metabolite SN-38 by High-Performance Liquid Chromatography: Application to Plasma Pharmacokinetic Studies in the Rat

Yang, Xiaoxia
Hu, Zeping
Chan, Sui Yung
Goh, Boon Cher
Duan, Wei
Chan, Eli
Zhou, Shufeng

July 2005

Irinotecan (CPT-11) and its main metabolite SN-38 are potent anticancer derivatives of camptothecin ...

Simultaneous determination of irinotecan (CPT-11) and SN-38 in tissue culture media and cancer cells by high performance liquid chromatography: Application to cellular metabolism and accumulation studies

Hu, ZP
Yang, XX
Chen, X
Chan, E
Duan, W
Zhou, SF

January 2007

A simple and sensitive HPLC method was developed to simultaneously determine CPT-11 and its major me...

Simultaneous determination of irinotecan (CPT-11) and SN-38 in tissue culture media and cancer cells by high performance liquid chromatography: application to cellular metabolism and accumulation studies

Hu, Z
Yang, X
Chen, X
Chan, E
Duan, W
Zhou, S

January 2007

A simple and sensitive HPLC method was developed to simultaneously determine CPT-11 and its major me...

Simultaneous determination of irinotecan (CPT-11) and SN-38 in tissue culture media and cancer cells by high performance liquid chromatography: Application to cellular metabolism and accumulation studies

Hu, Ze-Ping
Yang, Xiao-Xia
Chen, Xiao
Chan, Eli
Duan, Wei
Zhou, Shu-Feng

May 2007

A simple and sensitive HPLC method was developed to simultaneously determine CPT-11 and its major me...

Determination of irinotecan (CPT-11) and SN-38 in human whole blood and red blood cells by liquid chromatography with fluorescence detection

de Jong, FA (Floris)
Mathijssen, RHJ
de Bruijn, Peter
Loos, Walter
Verweij, Jaap
Sparreboom, A

October 2003

An analytical method was developed for the anticancer agent irinotecan (CPT-11) and its main metabol...

Simultaneous determination of the lactone and carboxylate forms of irinotecan (CPT-11) and its active metabolite SN-38 by high-performance liquid chromatography: Application to plasma pharmacokinetic studies in the rat

Yang, X.
Hu, Z.
Sui, Y.C.
Goh, B.C.
Duan, W.
Chan, E.
Zhou, S.

July 2005

Journal of Chromatography B: Analytical Technologies in the Biomedical and Life Sciences8212221-228J...

Simultaneous determination of the lactone and carboxylate forms of irinotecan (CPT-11) and its active metabolite SN-38 by high-performance liquid chromatography: Application to plasma pharmacokinetic studies in the rat

Yang, X.
Hu, Z.
Sui, Y.C.
Chan, E.
Zhou, S.
Goh, B.C.
Duan, W.

January 2005

10.1016/j.jchromb.2005.05.010Journal of Chromatography B: Analytical Technologies in the Biomedical ...

Simultaneous determination of the lactone and carboxylate forms of irinotecan (CPT-11) and its active metabolite SN-38 by high-performance liquid chromatography: Application to plasma pharmacokinetic studies in the rat

Yang, X.
Hu, Z.
Sui, Y.C.
Chan, E.
Zhou, S.
Goh, B.C.
Duan, W.

January 2005

Journal of Chromatography B: Analytical Technologies in the Biomedical and Life Sciences8212221-228J...

Bioanalytical method for the simultaneous quantification of irinotecan and its active metabolite SN-38 in mouse plasma and tissue homogenates using HPLC-fluorescence

Martínez-Chávez, Alejandra
Rosing, Hilde
Gan, Changpei
Wang, Yaogeng
Schinkel, Alfred H
Beijnen, Jos H

July 2020

A simple and rapid bioanalytical method was developed for the simultaneous quantification of irinote...

Bioanalytical method for the simultaneous quantification of irinotecan and its active metabolite SN-38 in mouse plasma and tissue homogenates using HPLC-fluorescence

Martínez-Chávez, Alejandra
Rosing, Hilde
Gan, Changpei
Wang, Yaogeng
Schinkel, Alfred H
Beijnen, Jos H

July 2020

A simple and rapid bioanalytical method was developed for the simultaneous quantification of irinote...

Bioanalytical method for the simultaneous quantification of irinotecan and its active metabolite SN-38 in mouse plasma and tissue homogenates using HPLC-fluorescence

Martínez-Chávez, Alejandra
Rosing, Hilde
Gan, Changpei
Wang, Yaogeng
Schinkel, Alfred H
Beijnen, Jos H
Afd Pharmacoepi & Clinical Pharmacology
Pharmacoepidemiology and Clinical Pharmacology

July 2020

A simple and rapid bioanalytical method was developed for the simultaneous quantification of irinote...

Bioanalytical method for the simultaneous quantification of irinotecan and its active metabolite SN-38 in mouse plasma and tissue homogenates using HPLC-fluorescence

Martínez-Chávez, Alejandra
Rosing, Hilde
Gan, Changpei
Wang, Yaogeng
Schinkel, Alfred H
Beijnen, Jos H

July 2020

A simple and rapid bioanalytical method was developed for the simultaneous quantification of irinote...

Simultaneous determination of irinotecan hydrochloride and its related compounds by high performance liquid chromatography using ultraviolet detection.

Mohammadi, A.
Esmaeili, F.
Dinarvand, R.
Atyabi, F.
Walker, R.B.

January 2010

A new simple, precise and accurate high performance liquid chromatography (HPLC) method was develope...

Simultaneous Determination of the Lactone and Carboxylate Forms of Irinotecan (CPT-11) and its Active Metabolite SN-38 by High-Performance Liquid Chromatography: Application to Plasma Pharmacokinetic Studies in the Rat

Yang, Xiaoxia
Hu, Zeping
Chan, Sui Yung
Goh, Boon Cher
Duan, Wei
Chan, Eli
Zhou, Shufeng

July 2005

Irinotecan (CPT-11) and its main metabolite SN-38 are potent anticancer derivatives of camptothecin ...

Simultaneous Determination of the Lactone and Carboxylate Forms of Irinotecan (CPT-11) and its Active Metabolite SN-38 by High-Performance Liquid Chromatography: Application to Plasma Pharmacokinetic Studies in the Rat

Yang, Xiaoxia
Hu, Zeping
Chan, Sui Yung
Goh, Boon Cher
Duan, Wei
Chan, Eli
Zhou, Shufeng

July 2005

Irinotecan (CPT-11) and its main metabolite SN-38 are potent anticancer derivatives of camptothecin ...

Simultaneous Determination of the Lactone and Carboxylate Forms of Irinotecan (CPT-11) and its Active Metabolite SN-38 by High-Performance Liquid Chromatography: Application to Plasma Pharmacokinetic Studies in the Rat

Yang, Xiaoxia
Hu, Zeping
Chan, Sui Yung
Goh, Boon Cher
Duan, Wei
Chan, Eli
Zhou, Shufeng

July 2005

Irinotecan (CPT-11) and its main metabolite SN-38 are potent anticancer derivatives of camptothecin ...

Simultaneous determination of irinotecan (CPT-11) and SN-38 in tissue culture media and cancer cells by high performance liquid chromatography: Application to cellular metabolism and accumulation studies

Hu, ZP
Yang, XX
Chen, X
Chan, E
Duan, W
Zhou, SF

January 2007

A simple and sensitive HPLC method was developed to simultaneously determine CPT-11 and its major me...

Simultaneous determination of irinotecan (CPT-11) and SN-38 in tissue culture media and cancer cells by high performance liquid chromatography: application to cellular metabolism and accumulation studies

Hu, Z
Yang, X
Chen, X
Chan, E
Duan, W
Zhou, S

January 2007

A simple and sensitive HPLC method was developed to simultaneously determine CPT-11 and its major me...

Simultaneous determination of irinotecan (CPT-11) and SN-38 in tissue culture media and cancer cells by high performance liquid chromatography: Application to cellular metabolism and accumulation studies

Hu, Ze-Ping
Yang, Xiao-Xia
Chen, Xiao
Chan, Eli
Duan, Wei
Zhou, Shu-Feng

May 2007

A simple and sensitive HPLC method was developed to simultaneously determine CPT-11 and its major me...

Determination of irinotecan (CPT-11) and SN-38 in human whole blood and red blood cells by liquid chromatography with fluorescence detection

de Jong, FA (Floris)
Mathijssen, RHJ
de Bruijn, Peter
Loos, Walter
Verweij, Jaap
Sparreboom, A

October 2003

An analytical method was developed for the anticancer agent irinotecan (CPT-11) and its main metabol...

Simultaneous determination of the lactone and carboxylate forms of irinotecan (CPT-11) and its active metabolite SN-38 by high-performance liquid chromatography: Application to plasma pharmacokinetic studies in the rat

Yang, X.
Hu, Z.
Sui, Y.C.
Goh, B.C.
Duan, W.
Chan, E.
Zhou, S.

July 2005

Journal of Chromatography B: Analytical Technologies in the Biomedical and Life Sciences8212221-228J...

Simultaneous determination of the lactone and carboxylate forms of irinotecan (CPT-11) and its active metabolite SN-38 by high-performance liquid chromatography: Application to plasma pharmacokinetic studies in the rat

Yang, X.
Hu, Z.
Sui, Y.C.
Chan, E.
Zhou, S.
Goh, B.C.
Duan, W.

January 2005

10.1016/j.jchromb.2005.05.010Journal of Chromatography B: Analytical Technologies in the Biomedical ...

Simultaneous determination of the lactone and carboxylate forms of irinotecan (CPT-11) and its active metabolite SN-38 by high-performance liquid chromatography: Application to plasma pharmacokinetic studies in the rat

Yang, X.
Hu, Z.
Sui, Y.C.
Chan, E.
Zhou, S.
Goh, B.C.
Duan, W.

January 2005

Journal of Chromatography B: Analytical Technologies in the Biomedical and Life Sciences8212221-228J...

Bioanalytical method for the simultaneous quantification of irinotecan and its active metabolite SN-38 in mouse plasma and tissue homogenates using HPLC-fluorescence

Martínez-Chávez, Alejandra
Rosing, Hilde
Gan, Changpei
Wang, Yaogeng
Schinkel, Alfred H
Beijnen, Jos H

July 2020

A simple and rapid bioanalytical method was developed for the simultaneous quantification of irinote...

Bioanalytical method for the simultaneous quantification of irinotecan and its active metabolite SN-38 in mouse plasma and tissue homogenates using HPLC-fluorescence

Martínez-Chávez, Alejandra
Rosing, Hilde
Gan, Changpei
Wang, Yaogeng
Schinkel, Alfred H
Beijnen, Jos H

July 2020

A simple and rapid bioanalytical method was developed for the simultaneous quantification of irinote...

Bioanalytical method for the simultaneous quantification of irinotecan and its active metabolite SN-38 in mouse plasma and tissue homogenates using HPLC-fluorescence

Martínez-Chávez, Alejandra
Rosing, Hilde
Gan, Changpei
Wang, Yaogeng
Schinkel, Alfred H
Beijnen, Jos H
Afd Pharmacoepi & Clinical Pharmacology
Pharmacoepidemiology and Clinical Pharmacology

July 2020

A simple and rapid bioanalytical method was developed for the simultaneous quantification of irinote...

Bioanalytical method for the simultaneous quantification of irinotecan and its active metabolite SN-38 in mouse plasma and tissue homogenates using HPLC-fluorescence

Martínez-Chávez, Alejandra
Rosing, Hilde
Gan, Changpei
Wang, Yaogeng
Schinkel, Alfred H
Beijnen, Jos H

July 2020

A simple and rapid bioanalytical method was developed for the simultaneous quantification of irinote...

Simultaneous determination of irinotecan hydrochloride and its related compounds by high performance liquid chromatography using ultraviolet detection.

Mohammadi, A.
Esmaeili, F.
Dinarvand, R.
Atyabi, F.
Walker, R.B.

January 2010

A new simple, precise and accurate high performance liquid chromatography (HPLC) method was develope...

Simultaneous Determination of the Lactone and Carboxylate Forms of Irinotecan (CPT-11) and its Active Metabolite SN-38 by High-Performance Liquid Chromatography: Application to Plasma Pharmacokinetic Studies in the Rat

Yang, Xiaoxia
Hu, Zeping
Chan, Sui Yung
Goh, Boon Cher
Duan, Wei
Chan, Eli
Zhou, Shufeng

July 2005

Irinotecan (CPT-11) and its main metabolite SN-38 are potent anticancer derivatives of camptothecin ...

Simultaneous Determination of the Lactone and Carboxylate Forms of Irinotecan (CPT-11) and its Active Metabolite SN-38 by High-Performance Liquid Chromatography: Application to Plasma Pharmacokinetic Studies in the Rat

Yang, Xiaoxia
Hu, Zeping
Chan, Sui Yung
Goh, Boon Cher
Duan, Wei
Chan, Eli
Zhou, Shufeng

July 2005

Irinotecan (CPT-11) and its main metabolite SN-38 are potent anticancer derivatives of camptothecin ...

Simultaneous Determination of the Lactone and Carboxylate Forms of Irinotecan (CPT-11) and its Active Metabolite SN-38 by High-Performance Liquid Chromatography: Application to Plasma Pharmacokinetic Studies in the Rat

Yang, Xiaoxia
Hu, Zeping
Chan, Sui Yung
Goh, Boon Cher
Duan, Wei
Chan, Eli
Zhou, Shufeng

July 2005

Irinotecan (CPT-11) and its main metabolite SN-38 are potent anticancer derivatives of camptothecin ...

Simultaneous determination of irinotecan (CPT-11) and SN-38 in tissue culture media and cancer cells by high performance liquid chromatography: Application to cellular metabolism and accumulation studies

Abstract

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Simultaneous determination of irinotecan (CPT-11) and SN-38 in tissue culture media and cancer cells by high performance liquid chromatography: Application to cellular metabolism and accumulation studies

Abstract

Extracted data

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