A case-control study of risk factors for intussusception among infants in eastern France after the introduction of the rotavirus vaccine
- Fotso Kamdem, Arnaud
- Vidal, Chrystelle
- Pazart, Lionel
- Leroux, Franck
- Pugin, Aurore
- Savet, Caroline
- Sainte-Claire Deville, Geoffroy
- Guillemot, Didier
- Massol, Jacques
DOIAbstract
International audienceObjectiveThe objective of the present study was to investigate the risk factors for intussusception (IS) among infants, including vaccination against rotavirus.MethodsCase-control study with systematic inclusion of all infants aged <1 year with suspected IS admitted to emergency departments in the eastern region of France between 1 April 2008 and 31 March 2012. All cases classed level 1 according to the Brighton classification were matched to 4 hospital controls. Two exposure windows were examined; exposure to the first dose of rotavirus vaccine in the 7 and in the 14 days prior to the occurrence of IS.ResultsA total of 115 cases were matched with 457 controls. The average vaccination coverage rate over the 4 years of ...
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