Analyze the scientific evidence on stress factors in nursing professionals who work in the Intensive Care Unit. It deals with a bibliographic review of the integrative literature review method, carried out in the months of November and December 2020. The search was carried out, through the Platform - VHL, using the databases (LILACS), (BDENF), and through Google Scholar Portal, adhering to the descriptors: “Stress”, “Nursing Professionals”, “Intensive Care Unit”, combined with the operator “Boolean”. Intensive Care Units demonstrate that nursing professionals who work in these environments face high levels of stress. There is a very close relationship between daily exposure to stressors related to the exhausting and tiring environment and s...