The isolates of Candida spp. and Cryptococcus neoformans were inhibited by curcumin, with different degrees of inhibition among species, with MICs ranging from 8-64 μg/mL. After exposure of the C. albicans strains to curcumin, it was observed a decrease in the number of viable cells and damage to cell membranes, the mitochondrial function of C. albicans cells appears to be affected after exposure to curcumin. Our data suggest that after exposure to curcumin, C. albicans cells showed total strand breaks in the DNA, where the nuclear DNA fragmentation was evident in the comet assay. Oxidative damage to DNA was verified by the alkaline comet assay in the presence of Fpg, where it was observed an increase in DNA migration of cells that...
Furazolidone (FZD), a synthetic nitrofuran derivative, has been widely used as an antibacterial and ...
<p>(A) A schematic diagram of the SSA system. Galactose was used to induce HO endonuclease to genera...
<p>HCT116 cells were treated with 20 µM curcumin or 5 µM 5-FU or a combination of 5 µM curcumin (4 h...
Considering that some therapeutic properties of curcumin are well described, so the present study po...
The cytotoxic activity of curcumin towards CCRF-CEM human T-cell leukemia cells was measured by the ...
Curcumin, a major pigment of turmeric, is a natural antioxidant possessing a variety of pharmacologi...
<p>(A) Cell cycle analysis of curcumin treated cells. TE-7 cells were treated with 30 µM of curcumin...
Curcumin is extensively used as a spice and pigment and has anticarcinogenic effects that could be l...
Current treatments for Candida albicans infection are limited due to the limited number of antifunga...
Introduction: Curcumin is the active ingredient in the traditional herbal remedy and dietary spice t...
[[abstract]]Curcumin, a major component of the Curcuma species, is known to have antioxidant, anti-i...
Curcumin, a polyphenol compound, has been recognized as a promising anti-cancer drug. The purpose of...
<p>(A) Wild-type cells (YMV045) or (B) <i>MRE11-MYC</i> cells (YAY032) were arrested at G2 with 15 μ...
<p>Cells were treated for 72 hours with 25 µM curcumin or were left untreated. HMW DNA damage was st...
Curcumin, a phytochemical derived from the rhizome of Curcuma longa, is a very potent inducer of can...
Furazolidone (FZD), a synthetic nitrofuran derivative, has been widely used as an antibacterial and ...
<p>(A) A schematic diagram of the SSA system. Galactose was used to induce HO endonuclease to genera...
<p>HCT116 cells were treated with 20 µM curcumin or 5 µM 5-FU or a combination of 5 µM curcumin (4 h...
Considering that some therapeutic properties of curcumin are well described, so the present study po...
The cytotoxic activity of curcumin towards CCRF-CEM human T-cell leukemia cells was measured by the ...
Curcumin, a major pigment of turmeric, is a natural antioxidant possessing a variety of pharmacologi...
<p>(A) Cell cycle analysis of curcumin treated cells. TE-7 cells were treated with 30 µM of curcumin...
Curcumin is extensively used as a spice and pigment and has anticarcinogenic effects that could be l...
Current treatments for Candida albicans infection are limited due to the limited number of antifunga...
Introduction: Curcumin is the active ingredient in the traditional herbal remedy and dietary spice t...
[[abstract]]Curcumin, a major component of the Curcuma species, is known to have antioxidant, anti-i...
Curcumin, a polyphenol compound, has been recognized as a promising anti-cancer drug. The purpose of...
<p>(A) Wild-type cells (YMV045) or (B) <i>MRE11-MYC</i> cells (YAY032) were arrested at G2 with 15 μ...
<p>Cells were treated for 72 hours with 25 µM curcumin or were left untreated. HMW DNA damage was st...
Curcumin, a phytochemical derived from the rhizome of Curcuma longa, is a very potent inducer of can...
Furazolidone (FZD), a synthetic nitrofuran derivative, has been widely used as an antibacterial and ...
<p>(A) A schematic diagram of the SSA system. Galactose was used to induce HO endonuclease to genera...
<p>HCT116 cells were treated with 20 µM curcumin or 5 µM 5-FU or a combination of 5 µM curcumin (4 h...