The effect of an oral lipid load on plasma lipids, apolipoproteins and lipoproteins.

by Siu-fan Fung.Thesis (M.Sc.)--Chinese University of Hong Kong, 1992.Includes bibliographical references (leaves 89-104).Title --- p.1Acknowledgement --- p.2Contents --- p.3Abstract --- p.6List of Tables --- p.9List of Figures --- p.12Reference Ranges --- p.14Abbreviations --- p.15Chapter 1. --- Introduction --- p.16Chapter 1.1. --- "Clinical biochemistry of lipids, apolipoproteins and lipoproteins" --- p.16Chapter 1.1.1. --- Lipids: definition and physiological importance --- p.16Chapter 1.1.2. --- Lipoproteins and apolipoproteins --- p.16Chapter 1.1.3. --- Lipoprotein metabolism --- p.19Chapter 1.1.3.1. --- Digestion and absorption of lipids --- p.19Chapter 1.1.3.2. --- Exogenous lipoprotein metabolism --- p.20Chapter 1.1.3.3. --- Endogenous lipoprotein metabolism --- p.21Chapter 1.1.4. --- Dyslipoproteinaemia and atherosclerosis --- p.22Chapter 1.1.4.1. --- Risk factos associated with atherosclerosis --- p.22Chapter 1.1.4.2. --- "Plasma cholesterol, lipoproteins and atherosclerosis" --- p.23Chapter 1.1.4.3. --- Plasma triglyceride and atherosclerosis --- p.25Chapter 1.1.4.4. --- "Apolipoprotein A-I (apo A-I), apolipoprotein B (apo B) and atherosclerosis" --- p.25Chapter 1.1.4.5. --- Postprandial lipidaemia and atherosclerosis --- p.26Chapter 1.2. --- Lipid metabolism in diabetes mellitus --- p.29Chapter 1.2.1. --- Diabetes mellitus --- p.29Chapter 1.2.2. --- Lipoprotein metabolism in non-insulin dependent diabetes mellitus ( NIDDM ) --- p.30Chapter 1.3. --- Lipid tolerance test --- p.32Chapter 1.3.1. --- General discussion --- p.32Chapter 1.3.2. --- Use of Maxolon --- p.33Chapter 1.4. --- Objectives --- p.34Chapter 2. --- Materials and methods --- p.36Chapter 2.1 --- Materials --- p.36Chapter 2.2 --- Subjects and patients --- p.37Chapter 2.2.1. --- Healthy subjects --- p.37Chapter 2.2.2. --- NIDDM patients --- p.37Chapter 2.2.3. --- Glucose intolerant (IGT) patients --- p.37Chapter 2.2.4 --- Study design --- p.38Chapter 2.3. --- Blood samples --- p.39Chapter 2.3.1. --- Serum samples --- p.39Chapter 2.3.2. --- Serum triglyceride-rich lipoproteins (TRL) fraction --- p.39Chapter 2.4. --- Analytical methods --- p.40Chapter 2.4.1. --- Cholesterol --- p.40Chapter 2.4.2. --- Triglyceride --- p.40Chapter 2.4.3. --- HDL-cholesterol --- p.41Chapter 2.4.4. --- Apo A-1 and Apo-B --- p.41Chapter 2.5. --- Measurement of postprandial serum triglyceride and TRL triglyceride --- p.42Chapter 2.6. --- Statistical analysis --- p.42Chapter 3. --- Results --- p.44Chapter 4. --- Discussion --- p.78References --- p.8