During primary axis development in vertebrates, Hox genes are deployed in a collinear fashion, where the order in which they are present on the chromosome is the order in which they are expressed in the organism. During development of secondary axes, the same order will end up determining emerging pectoral fins and homologous limbs, but as these appendages differentiate, an alternate regulatory sequence unfolds. There is an inversion in the expression pattern of the posterior HoxD genes, where the most posterior gene shifts from the most restricted to the least restricted expression domain relative to neighboring genes, with anterior expansion. This pattern is referred to as inverse collinearity (IC) and has been established for pectoral fi...
The pectoral fins of ancestral fishes had multiple proximal elements connected to their pectoral gir...
© The Author(s), 2021. This article is distributed under the terms of the Creative Commons Attributi...
Of the many unique chronicles of development and paleontology, none are so compelling as the transit...
International audienceThe role of Homeobox transcription factors during fin and limb development hav...
The role of Homeobox transcription factors during fin and limb development have been the focus of re...
AbstractDuring development of the limbs, Hox genes belonging to the paralogous groups 9–13 are expre...
The evolutionary transition of fins to limbs involved development of a new suite of distal skeletal ...
Hox genes are essential for growth and patterning of the tetrapod limb skeleton. Mice mutant for the...
The axial skeleton of tetrapods is organized into distinct anteroposterior regions of the vertebral ...
Understanding the patterning mechanisms that operate to promote differentiation of individual segmen...
Recent fossil finds and experimental analysis of chick and mouse embryos highlighted the lateral fin...
The evolutionary origin of the autopod involved a loss of the fin-fold and associated dermal skeleto...
Throughout evolution, vertebrates have adapted to aquatic and terrestrial environments, developing a...
AbstractComparisons between Hox gene expression patterns in teleost fins and tetrapod limbs are reve...
Background: The concerted activity of Meis and Hoxa11 transcription factors is essential for the sub...
The pectoral fins of ancestral fishes had multiple proximal elements connected to their pectoral gir...
© The Author(s), 2021. This article is distributed under the terms of the Creative Commons Attributi...
Of the many unique chronicles of development and paleontology, none are so compelling as the transit...
International audienceThe role of Homeobox transcription factors during fin and limb development hav...
The role of Homeobox transcription factors during fin and limb development have been the focus of re...
AbstractDuring development of the limbs, Hox genes belonging to the paralogous groups 9–13 are expre...
The evolutionary transition of fins to limbs involved development of a new suite of distal skeletal ...
Hox genes are essential for growth and patterning of the tetrapod limb skeleton. Mice mutant for the...
The axial skeleton of tetrapods is organized into distinct anteroposterior regions of the vertebral ...
Understanding the patterning mechanisms that operate to promote differentiation of individual segmen...
Recent fossil finds and experimental analysis of chick and mouse embryos highlighted the lateral fin...
The evolutionary origin of the autopod involved a loss of the fin-fold and associated dermal skeleto...
Throughout evolution, vertebrates have adapted to aquatic and terrestrial environments, developing a...
AbstractComparisons between Hox gene expression patterns in teleost fins and tetrapod limbs are reve...
Background: The concerted activity of Meis and Hoxa11 transcription factors is essential for the sub...
The pectoral fins of ancestral fishes had multiple proximal elements connected to their pectoral gir...
© The Author(s), 2021. This article is distributed under the terms of the Creative Commons Attributi...
Of the many unique chronicles of development and paleontology, none are so compelling as the transit...