Monócitos podem ser classificados em três subgrupos de acordo com o nível de expressão dos marcadores CD14 e CD16. Monócitos clássicos são os mais abundantes no sangue. Eles expressam um fenótipo CD14+CD16-CCR2+, conferindo a eles a habilidade de migrar rapidamente a sítios inflamatórios, através da resposta à quimiocina CCL2 (CC chemokine ligand 2). Aqui apresentamos a identificação e caracterização de uma expansão de um novo subgrupo de monócitos durante a infecção por SIV e HIV. Essas células são indistinguíveis dos monócitos clássicos quanto à expressão de CD14 e CD16; porém não expressam CCR2 de superfície. A análise do transcriptoma de células selecionadas confirmou que elas representam uma subpopulação distinta que expressa níveis ma...
Monocytes are increasingly implicated in the inflammatory consequences of HIV-1 disease, yet their p...
International audienceHIV infects activated CD4⁺ T cells and induces their depletion. Progressive HI...
HIV-2 infection is characterized by low viremia and slow disease progression as compared to HIV-1 in...
Monócitos podem ser classificados em três subgrupos de acordo com o nível de expressão dos marcadore...
Monocytes have been categorized in three main subpopulations based on CD14 and CD16 surface expressi...
<p>(<b>A</b>) HIV infected and uninfected monocytes from 5 independent individuals, enriched for the...
Thesis (MScMedSc) –Stellenbosch University, 2014.ENGLISH ABSTRACT: HIV-infection is characterized by...
<p>(A) PBMC from AIDS subjects were stained with fluorochrome-conjugated Abs. CD14 and CD16 expressi...
<p>“Day 3” monocytes from 8 separate individuals were infected with HIV or remained uninfected as de...
O sistema complemento apresenta imaturidade funcional em crianças mais jovens, com o sistema imune i...
<p><b>A)</b> PBMC and liver cell suspensions were first gating on single, live, CD45+ cells followed...
functionally similar to myeloid-derived suppressor cells during SIV and HIV infectio
Monocytes are increasingly implicated in the inflammatory consequences of HIV-1 disease, yet their p...
International audienceHIV-2 infection is characterized by low viremia and slow disease progression a...
International audienceDespite early antiretroviral therapy (ART), treatment interruption is associat...
Monocytes are increasingly implicated in the inflammatory consequences of HIV-1 disease, yet their p...
International audienceHIV infects activated CD4⁺ T cells and induces their depletion. Progressive HI...
HIV-2 infection is characterized by low viremia and slow disease progression as compared to HIV-1 in...
Monócitos podem ser classificados em três subgrupos de acordo com o nível de expressão dos marcadore...
Monocytes have been categorized in three main subpopulations based on CD14 and CD16 surface expressi...
<p>(<b>A</b>) HIV infected and uninfected monocytes from 5 independent individuals, enriched for the...
Thesis (MScMedSc) –Stellenbosch University, 2014.ENGLISH ABSTRACT: HIV-infection is characterized by...
<p>(A) PBMC from AIDS subjects were stained with fluorochrome-conjugated Abs. CD14 and CD16 expressi...
<p>“Day 3” monocytes from 8 separate individuals were infected with HIV or remained uninfected as de...
O sistema complemento apresenta imaturidade funcional em crianças mais jovens, com o sistema imune i...
<p><b>A)</b> PBMC and liver cell suspensions were first gating on single, live, CD45+ cells followed...
functionally similar to myeloid-derived suppressor cells during SIV and HIV infectio
Monocytes are increasingly implicated in the inflammatory consequences of HIV-1 disease, yet their p...
International audienceHIV-2 infection is characterized by low viremia and slow disease progression a...
International audienceDespite early antiretroviral therapy (ART), treatment interruption is associat...
Monocytes are increasingly implicated in the inflammatory consequences of HIV-1 disease, yet their p...
International audienceHIV infects activated CD4⁺ T cells and induces their depletion. Progressive HI...
HIV-2 infection is characterized by low viremia and slow disease progression as compared to HIV-1 in...