Nutritional and metabolic disorders caused by antiretroviral therapy and nutritional approach : a narrative review.

Submitted by Maurílio Figueiredo (maurilioafigueiredo@yahoo.com.br) on 2015-12-11T18:09:12Z No. of bitstreams: 1 ARTIGO_DisturbiosNutricionaisMetabólicos.pdf: 58738 bytes, checksum: f0925b9b52323717513d5a42d6321ed7 (MD5)Approved for entry into archive by Oliveira Flávia (flavia@sisbin.ufop.br) on 2015-12-14T17:16:43Z (GMT) No. of bitstreams: 1 ARTIGO_DisturbiosNutricionaisMetabólicos.pdf: 58738 bytes, checksum: f0925b9b52323717513d5a42d6321ed7 (MD5)Made available in DSpace on 2015-12-14T17:16:43Z (GMT). No. of bitstreams: 1 ARTIGO_DisturbiosNutricionaisMetabólicos.pdf: 58738 bytes, checksum: f0925b9b52323717513d5a42d6321ed7 (MD5) Previous issue date: 2015O uso da terapia antirretroviral (TARV) tem aumentado a sobrevida das pessoas vivendo com HIV/AIDS (PVHA) alterando consideravelmente a historia natural da infecção. Entretanto, em alguns casos, o uso destes medicamentos tem sido associado a distúrbios nutricionais e metabólicos. O objetivo deste estudo foi descrever os distúrbios nutricionais e metabólicos ocasionados pelo uso da TARV e o respectivo papel terapêutico, da abordagem nutricional em PVHA. Trata-se de uma revisão narrativa, realizada durante o segundo semestre do ano de 2012, utilizando os seguintes descritores: AIDS, HIV, PVHA, TARV, estado nutricional, acompanhamento nutricional. O principal distúrbio nutricional encontrado nesta revisão, relacionado ao uso de TARV, foi a síndrome lipodistrofica associada a dislipidemias e hiperglicemias, bem como, alterações ósseas e aumento de gordura corporal. Neste sentido, o acompanhamento nutricional e extremamente importante para a melhora da qualidade de vida e prevenção de demais complicações metabólicas em PVHA.The use of antiretroviral therapy has increased the survival of people living with HIV/AIDS considerably altering the natural history of infection. However, insome cases, the use of these drugs have been associated with nutritional and metabolic disorders. The objective of this study was to describe the nutritional and metabolic disorders caused by antiretroviral therapy and their therapeutic role of nutritional approach for people living with HIV/AIDS. This is a narrative review, conducted during the second half of 2012, using the following descriptors: AIDS, HIV, people living with HIV/AIDS, antiretroviral therapy, nutritional status, nutritional counseling. The main nutritional disorder found in this review, related to the use of antiretroviral therapy was the lipodystrophy syndrome associated with dyslipidemia and hyperglycemia, as well as bone changes and increase in body fat. In this sense, the nutritional monitoring is extremely important to improve the quality of life and prevention of other metabolic complications in people living with HIV/AIDS