This paper proposes to analyze essential points about Freud’s demarche (mode of procedure) in the theoretical construction of transference. The aim, based on Freud’s original ideas is to identify the origin of the transference phenomenon, which, in his clinical scenario, became one of his fundamental conceptions. For that purpose, a literature review was carried out to investigate the epistemology of Freud’s ideas, his models as well as the physicochemical-energetic referents. Such models and referents constituted the structure of Freud’s methodological foundation in the development of the metapsychology, which, in turn, became one of the references to understand the transference phenomenon. The present paper may contribute to the research ...