Trypanosoma rangeli: a new perspective for studying the modulation of immune reactions of Rhodnius prolixus

Submitted by Jonathan Barbosa (jon_crf@hotmail.com) on 2012-02-28T16:23:17Z No. of bitstreams: 1 Garcia1_2009.pdf: 412802 bytes, checksum: 1bc5f3760d5b71a5cea63e7f457e83cf (MD5)Rejected by Catarina Soares(cfsoares@inmetro.gov.br), reason: Corrigir nomes dos autores na referencia bibliografica on 2012-03-15T18:15:43Z (GMT)Submitted by Jonathan Barbosa (jon_crf@hotmail.com) on 2012-03-16T12:54:57Z No. of bitstreams: 1 Garcia1_2009.pdf: 412802 bytes, checksum: 1bc5f3760d5b71a5cea63e7f457e83cf (MD5)Approved for entry into archive by Regina Mello(mrmello@inmetro.gov.br) on 2012-06-28T16:57:32Z (GMT) No. of bitstreams: 1 Garcia1_2009.pdf: 412802 bytes, checksum: 1bc5f3760d5b71a5cea63e7f457e83cf (MD5)Made available in DSpace on 2012-08-13T12:57:10Z (GMT). No. of bitstreams: 1 Garcia1_2009.pdf: 412802 bytes, checksum: 1bc5f3760d5b71a5cea63e7f457e83cf (MD5) Previous issue date: 2009Insects are exposed to a wide range of microorganisms (bacteria, fungi, parasites and viruses) and have interconnected powerful immune reactions. Although insects lack an acquired immune system they have well-developed innate immune defences that allow a general and rapid response to infectious agents. Over the last few decades we have observed a dramatic increase in the knowledge of insect innate immunity, which relies on both humoral and cellular responses. However, innate reactions to natural insect pathogens and insect-transmitted pathogens, such as parasites, still remain poorly understood. In this review, we briefly introduce the general immune system of insects and highlight our current knowledge of these reactions focusing on the interactions of Trypanosoma rangeli with Rhodnius prolixus, an important model for innate immunity investigation.10 p. : il