mammals, the circadian oscillators that drive daily behavioral and endocrine rhythms are located in the hypothalamic suprachiasmatic nucleus (SCN). While the SCN is anatomically well-situated to receive and transmit temporal cues to the rest of the brain and periphery, there are many holes in our understanding of how this temporal regulation occurs. Unanswered questions include how cell autonomous circadian oscillations within the SCN remain synchronized to each other as well as communicate temporal information to downstream targets. In recent years, it has become clear that neuropeptides are critically involved in circadian timekeeping. One such neuropeptide, vasoactive intestinal peptide (VIP), defines a cell population within the SCN...
Abstract Many mammalian cell types show daily rhythms in gene expression driven by a circadian pacem...
Circadian rhythms in physiology and behavior are coordinated by the brain's dominant circadian pacem...
Circadian rhythms are programmed by the suprachiasmatic nucleus (SCN), which relies on neuropeptide ...
Biological oscillations with an endogenous period of near 24 h (circadian rhythms) are generated by ...
Circadian rhythms affect human health and well-being by temporally organizing biological processes a...
The neuropeptide vasoactive intestinal peptide (VIP) is expressed at high levels in a subset of neur...
The suprachiasmatic nucleus (SCN), the master circadian pacemaker in mammals, is located ...
Circadian rhythms in physiology and behavior are coordinated by the brain's dominant circadian pacem...
The neuropeptide vasoactive intestinal peptide (VIP) is expressed at high levels in the neurons of t...
In mammalian hypothalamus, the suprachiasmatic nucleus: SCN) generates daily behavioral and physiolo...
Shift work or transmeridian travel can desynchronize the body's circadian rhythms from local light-d...
Robust synchronization is a critical feature of several systems including the mammalian circadian cl...
Individual neurons in the suprachiasmatic nuclei (SCN) contain an intracellular molecular clock and ...
Circadian activity modulation in the suprachiasmatic nucleus (SCN) is a network-level emergent prope...
Intercellular signaling has emerged as a key process enabling autonomous cellular oscillators within...
Abstract Many mammalian cell types show daily rhythms in gene expression driven by a circadian pacem...
Circadian rhythms in physiology and behavior are coordinated by the brain's dominant circadian pacem...
Circadian rhythms are programmed by the suprachiasmatic nucleus (SCN), which relies on neuropeptide ...
Biological oscillations with an endogenous period of near 24 h (circadian rhythms) are generated by ...
Circadian rhythms affect human health and well-being by temporally organizing biological processes a...
The neuropeptide vasoactive intestinal peptide (VIP) is expressed at high levels in a subset of neur...
The suprachiasmatic nucleus (SCN), the master circadian pacemaker in mammals, is located ...
Circadian rhythms in physiology and behavior are coordinated by the brain's dominant circadian pacem...
The neuropeptide vasoactive intestinal peptide (VIP) is expressed at high levels in the neurons of t...
In mammalian hypothalamus, the suprachiasmatic nucleus: SCN) generates daily behavioral and physiolo...
Shift work or transmeridian travel can desynchronize the body's circadian rhythms from local light-d...
Robust synchronization is a critical feature of several systems including the mammalian circadian cl...
Individual neurons in the suprachiasmatic nuclei (SCN) contain an intracellular molecular clock and ...
Circadian activity modulation in the suprachiasmatic nucleus (SCN) is a network-level emergent prope...
Intercellular signaling has emerged as a key process enabling autonomous cellular oscillators within...
Abstract Many mammalian cell types show daily rhythms in gene expression driven by a circadian pacem...
Circadian rhythms in physiology and behavior are coordinated by the brain's dominant circadian pacem...
Circadian rhythms are programmed by the suprachiasmatic nucleus (SCN), which relies on neuropeptide ...