Topics
homeostasisBuilding
bipolar disorderDisease
acantholysisDisease
autosomal dominantDisease
hyperkeratoticDisease
calciumChemical substance
We present a 58-year-old woman with bipolardisorder and with a longstanding history of yellowbrown,hyperkeratotic papules in a seborrheicdistribution and nail changes. Her father andpaternal grandmother had similar eruptions and alsohad psychiatric disease. Histopathologic examinationshowed acantholysis and dyskeratosis, which wasconsistent with Darier-White disease. Darier-Whitedisease is a rare, hereditary disorder that is inheritedin an autosomal dominant manner and that usuallypresents in adolescence or early adulthood dueto mutations in the SERCA2 calcium pump. Theresultant alterations in calcium homeostasis affectdesmosome assembly and lead to acantholysis andapoptosis, which creates the characteristic eruption.Genetic linkage analysi...
Objectives Darier disease is an autosomal dominant skin disorder caused by mutations in the ATPase,...
Darier disease (DD) is a rare dominantly inherited genodermatosis characterized by loss of intercell...
Darier's disease is a rare autosomal dominant skin disorder in which there is abnormal adhesion betw...
Darier's disease is a rare autosomal dominantly inherited keratosis.1 We have previously reported a ...
Follicular dyskeratosis (Darier-White disease) is a hereditary skin disease that is extremely rare i...
Introduction . Darier’s disease (dyskeratosis follicularis, keratosis follicularis, Darier-White dis...
Darier disease is an autosomal dominant blistering disorder linked to mutation of the endoplasmic re...
Darier disease, also known as Darier-White disease, is characterized by yellow to brown, oily kerato...
Darier disease is a rare autosomal dominant disorder that results from a mutation in the gene coding...
Darier-White disease (keratosis follicularis) is a rare disorder of keratinization involving the epi...
Bipolar affective disorder is a genetically complex psychiatric disorder with a population prevalenc...
Darier disease (DD) is a severe, inherited dermatological disorder with a characteristic clinical a...
Darier's disease is a rare autosomal dominantly inherited keratosis. This is an account of one famil...
Darier disease, also known as keratosis follicularis, dyskeratosis follicularis, and benign dyskerat...
Darier\u27s disease is an inherited dermatitis that is due to a mutation in the ATP2A2 gene. This mu...
Objectives Darier disease is an autosomal dominant skin disorder caused by mutations in the ATPase,...
Darier disease (DD) is a rare dominantly inherited genodermatosis characterized by loss of intercell...
Darier's disease is a rare autosomal dominant skin disorder in which there is abnormal adhesion betw...
Darier's disease is a rare autosomal dominantly inherited keratosis.1 We have previously reported a ...
Follicular dyskeratosis (Darier-White disease) is a hereditary skin disease that is extremely rare i...
Introduction . Darier’s disease (dyskeratosis follicularis, keratosis follicularis, Darier-White dis...
Darier disease is an autosomal dominant blistering disorder linked to mutation of the endoplasmic re...
Darier disease, also known as Darier-White disease, is characterized by yellow to brown, oily kerato...
Darier disease is a rare autosomal dominant disorder that results from a mutation in the gene coding...
Darier-White disease (keratosis follicularis) is a rare disorder of keratinization involving the epi...
Bipolar affective disorder is a genetically complex psychiatric disorder with a population prevalenc...
Darier disease (DD) is a severe, inherited dermatological disorder with a characteristic clinical a...
Darier's disease is a rare autosomal dominantly inherited keratosis. This is an account of one famil...
Darier disease, also known as keratosis follicularis, dyskeratosis follicularis, and benign dyskerat...
Darier\u27s disease is an inherited dermatitis that is due to a mutation in the ATP2A2 gene. This mu...
Objectives Darier disease is an autosomal dominant skin disorder caused by mutations in the ATPase,...
Darier disease (DD) is a rare dominantly inherited genodermatosis characterized by loss of intercell...
Darier's disease is a rare autosomal dominant skin disorder in which there is abnormal adhesion betw...
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