DNA methylation is a heritable epigenetic modification involved in gene silencing, imprinting, and the suppression of retrotransposons. Global DNA demethylation occurs in the early embryo and the germ line, and may be mediated by Tet (ten eleven transloca
One of the main regulators of gene expression during embryogenesis and stem cell differentiation is ...
Cytosine methylation is found in the genomes of many plants and animals and has been associated with...
DNA methylation at the C-5 position of cytosine (5mC) is one of the best-studied epigenetic modifica...
DNA methylation is a heritable epigenetic modification involved in gene silencing, imprinting, and t...
Histone methylation patterns regulate gene expression and are highly dynamic during development. The...
Abstract Background Histone methylation patterns regulate gene expression and are highly dynamic dur...
Development is often assumed to be hardwired in the genome, but several lines of evidence indicate t...
There is a growing appreciation that environmental factors can impact embryonic development and prog...
Abstract Background Accurate regulation of DNA methylation is necessary for normal cells to differen...
Vitamin C (ascorbate) is a widely used medium supplement in embryonic stem cell culture. Here, we sh...
Cytosine methylation, normally found on cytosine residues adjacent to guanine (i.e., a CpG dinucleot...
TET proteins have been found to play an important role in active demethylation at CpG sites in mamma...
SummaryPrimordial germ cells (PGCs) undergo dramatic rearrangements to their methylome during embryo...
Background Accurate regulation of DNA methylation is necessary for normal cells to differentiate, de...
AbstractTET proteins have been found to play an important role in active demethylation at CpG sites ...
One of the main regulators of gene expression during embryogenesis and stem cell differentiation is ...
Cytosine methylation is found in the genomes of many plants and animals and has been associated with...
DNA methylation at the C-5 position of cytosine (5mC) is one of the best-studied epigenetic modifica...
DNA methylation is a heritable epigenetic modification involved in gene silencing, imprinting, and t...
Histone methylation patterns regulate gene expression and are highly dynamic during development. The...
Abstract Background Histone methylation patterns regulate gene expression and are highly dynamic dur...
Development is often assumed to be hardwired in the genome, but several lines of evidence indicate t...
There is a growing appreciation that environmental factors can impact embryonic development and prog...
Abstract Background Accurate regulation of DNA methylation is necessary for normal cells to differen...
Vitamin C (ascorbate) is a widely used medium supplement in embryonic stem cell culture. Here, we sh...
Cytosine methylation, normally found on cytosine residues adjacent to guanine (i.e., a CpG dinucleot...
TET proteins have been found to play an important role in active demethylation at CpG sites in mamma...
SummaryPrimordial germ cells (PGCs) undergo dramatic rearrangements to their methylome during embryo...
Background Accurate regulation of DNA methylation is necessary for normal cells to differentiate, de...
AbstractTET proteins have been found to play an important role in active demethylation at CpG sites ...
One of the main regulators of gene expression during embryogenesis and stem cell differentiation is ...
Cytosine methylation is found in the genomes of many plants and animals and has been associated with...
DNA methylation at the C-5 position of cytosine (5mC) is one of the best-studied epigenetic modifica...