Add to ORKGT-cell receptor (TCR) phosphorylation is controlled by a complex network that includes Lck, a Src family kinase (SFK), the tyrosine phosphatase CD45 and the Lck-inhibitory kinase Csk. How these competing phosphorylation and dephosphorylation reactions ar
T cell activation by antigens binding to the T cell receptor (TCR) must be properly regulated to ens...
Src-family kinases are critical members of many signalling pathways present in many cell types. Lck,...
T-cell development in the thymus and activation of mature T cells in secondary lymphoid organs requi...
AbstractThe TCR signal transduction is initiated by the activation of Src-family kinases (SFK) which...
Although the biochemical events induced by T-cell receptor (TCR) triggering have been well studied, ...
Lck is a Src-family tyrosine kinase whose activity is essential for T cell activation and developme...
Exactly how ligand binding 'triggers' T cell receptor (TCR) phosphorylation is unclear. It has been ...
Receptor phosphorylation is thought to be tightly regulated because phosphorylated receptors initiat...
Receptor phosphorylation is thought to be tightly regulated because phosphorylated receptors initiat...
Exactly how ligand binding 'triggers' T cell receptor (TCR) phosphorylation is unclear. It has been ...
A T-cell-mediated immune response is initiated by the T-cell receptor (TCR) interacting with peptide...
T cell signaling begins with the ligation of the T cell antigen receptor (TCR) by a cognate peptide ...
Tyrosine phosphorylation is one of the key covalent modifications that occur in multicellular organi...
T cell activation by antigens binding to the T cell receptor (TCR) must be properly regulated to ens...
T-cell development in the thymus and activation of mature T cells in secondary lymphoid organs requi...
T cell activation by antigens binding to the T cell receptor (TCR) must be properly regulated to ens...
Src-family kinases are critical members of many signalling pathways present in many cell types. Lck,...
T-cell development in the thymus and activation of mature T cells in secondary lymphoid organs requi...
AbstractThe TCR signal transduction is initiated by the activation of Src-family kinases (SFK) which...
Although the biochemical events induced by T-cell receptor (TCR) triggering have been well studied, ...
Lck is a Src-family tyrosine kinase whose activity is essential for T cell activation and developme...
Exactly how ligand binding 'triggers' T cell receptor (TCR) phosphorylation is unclear. It has been ...
Receptor phosphorylation is thought to be tightly regulated because phosphorylated receptors initiat...
Receptor phosphorylation is thought to be tightly regulated because phosphorylated receptors initiat...
Exactly how ligand binding 'triggers' T cell receptor (TCR) phosphorylation is unclear. It has been ...
A T-cell-mediated immune response is initiated by the T-cell receptor (TCR) interacting with peptide...
T cell signaling begins with the ligation of the T cell antigen receptor (TCR) by a cognate peptide ...
Tyrosine phosphorylation is one of the key covalent modifications that occur in multicellular organi...
T cell activation by antigens binding to the T cell receptor (TCR) must be properly regulated to ens...
T-cell development in the thymus and activation of mature T cells in secondary lymphoid organs requi...
T cell activation by antigens binding to the T cell receptor (TCR) must be properly regulated to ens...
Src-family kinases are critical members of many signalling pathways present in many cell types. Lck,...
T-cell development in the thymus and activation of mature T cells in secondary lymphoid organs requi...