Add to ORKGStudies of coat color mutants have greatly contributed to the discovery of genes that regulate melanocyte development and function. Here, we generated Yy1 conditional knockout mice in the melanocyte-lineage and observed profound melanocyte deficiency and
Ying Yang 1 (YY1) is a multifunctional transcription factor that plays important roles in gene regul...
YY1 is a multifunctional zinc finger transcription factor that regulates activation, repression and ...
Melanocortin Receptor 1 (Mc1r) signaling is essential for proper pigment production. In its absence,...
<div><p>Studies of coat color mutants have greatly contributed to the discovery of genes that regula...
<p>(A,E) Knockdown of endogenous YY1 (A) and MITF (E) in MALME-3M cells. MALME-3M cells were infecte...
<p>(A) Skin and hair pigmentation phenotype of <i>TyrCre, yy1f/fl</i> in the first (P4, P10) and sec...
The diversity of hair and skin color is a direct result of melanin synthesis occurring in melanocyte...
Deregulation of cellular metabolism through metabolic rewiring and translational reprogramming are c...
Increasing evidence suggests that cancer cells highjack developmental programs for disease initiatio...
The tyrosinase family comprises three members, tyrosinase (Tyr), tyrosinase-related protein 1 (Tyrp1...
The slaty (slt) mutation is known to reduce the activity of dopachrome tautomerase (Dct)/tyrosinase ...
The coat color of C57BL/6-Mitfvit/vit mice whitens with age, because of a one-nucleotide mutation in...
AbstractMelanocytes, the pigment-producing cells, arise from multipotent neural crest (NC) cells dur...
<p>(A) Scatter plot of mean log fold-changes in MALME-3M and UACC62 cells treated with MITF shRNA (s...
In this article we describe the rapid advances made in the molecular genetics of three inherited pig...
Ying Yang 1 (YY1) is a multifunctional transcription factor that plays important roles in gene regul...
YY1 is a multifunctional zinc finger transcription factor that regulates activation, repression and ...
Melanocortin Receptor 1 (Mc1r) signaling is essential for proper pigment production. In its absence,...
<div><p>Studies of coat color mutants have greatly contributed to the discovery of genes that regula...
<p>(A,E) Knockdown of endogenous YY1 (A) and MITF (E) in MALME-3M cells. MALME-3M cells were infecte...
<p>(A) Skin and hair pigmentation phenotype of <i>TyrCre, yy1f/fl</i> in the first (P4, P10) and sec...
The diversity of hair and skin color is a direct result of melanin synthesis occurring in melanocyte...
Deregulation of cellular metabolism through metabolic rewiring and translational reprogramming are c...
Increasing evidence suggests that cancer cells highjack developmental programs for disease initiatio...
The tyrosinase family comprises three members, tyrosinase (Tyr), tyrosinase-related protein 1 (Tyrp1...
The slaty (slt) mutation is known to reduce the activity of dopachrome tautomerase (Dct)/tyrosinase ...
The coat color of C57BL/6-Mitfvit/vit mice whitens with age, because of a one-nucleotide mutation in...
AbstractMelanocytes, the pigment-producing cells, arise from multipotent neural crest (NC) cells dur...
<p>(A) Scatter plot of mean log fold-changes in MALME-3M and UACC62 cells treated with MITF shRNA (s...
In this article we describe the rapid advances made in the molecular genetics of three inherited pig...
Ying Yang 1 (YY1) is a multifunctional transcription factor that plays important roles in gene regul...
YY1 is a multifunctional zinc finger transcription factor that regulates activation, repression and ...
Melanocortin Receptor 1 (Mc1r) signaling is essential for proper pigment production. In its absence,...