Add to ORKGNMR and MD simulations have demonstrated that the flaps of HIV-1 protease (HIV-1p) adopt a range of conformations that are coupled with its enzymatic activity. Previously, a model was created for an allosteric site located between the flap and the core o
Motivation: HIV-1 protease is a key drug target due to its role in the life cycle of the HIV-1 virus...
AbstractThe crystal structure of HIV-1 protease with an inhibitor has been compared with the structu...
Human immunodeficiency virus type 1 (HIV-1) protease (PR) permits viral maturation by processing the...
NMR and MD simulations have demonstrated that the flaps of HIV-1 protease (HIV-1p) adopt a range of ...
The protease from type I human immunodeficiency virus (HIV-1 ) is a critical drug target against whi...
BACKGROUND: The human immunodeficiency virus type 1 (HIV-1) protease is an essential viral protein t...
The emergence of drug-resistant mutants of HIV-1 is a tragic effect associated with conventional lon...
The emergence of drug-resistant mutants of HIV-1 is a tragic effect associated with conventional lon...
Human immunodeficiency virus type 1 protease (HIV-1 PR) is an essential enzyme in the HIV-1 life cy...
Human immunodeficiency virus type 1 protease (HIV-1 PR) is an essential enzyme in the HIV-1 life cy...
We present a rigidity analysis on a large number of X-ray crystal structures of the enzyme HIV-1 pro...
Human immunodeficiency virus type 1 (HIV-1) protease processes and cleaves the Gag and Gag-Pol polyp...
HIV-1 protease (PR) permits viral maturation by processing the Gag and Gag-Pro-Pol polyproteins. Tho...
A recent crystal structure of HIV‐1 protease (HIVp) was the first to experimentally observe a ligand...
We present the discovery of low molecular weight inhibitors of human immunodeficiency virus 1 (HIV-1...
Motivation: HIV-1 protease is a key drug target due to its role in the life cycle of the HIV-1 virus...
AbstractThe crystal structure of HIV-1 protease with an inhibitor has been compared with the structu...
Human immunodeficiency virus type 1 (HIV-1) protease (PR) permits viral maturation by processing the...
NMR and MD simulations have demonstrated that the flaps of HIV-1 protease (HIV-1p) adopt a range of ...
The protease from type I human immunodeficiency virus (HIV-1 ) is a critical drug target against whi...
BACKGROUND: The human immunodeficiency virus type 1 (HIV-1) protease is an essential viral protein t...
The emergence of drug-resistant mutants of HIV-1 is a tragic effect associated with conventional lon...
The emergence of drug-resistant mutants of HIV-1 is a tragic effect associated with conventional lon...
Human immunodeficiency virus type 1 protease (HIV-1 PR) is an essential enzyme in the HIV-1 life cy...
Human immunodeficiency virus type 1 protease (HIV-1 PR) is an essential enzyme in the HIV-1 life cy...
We present a rigidity analysis on a large number of X-ray crystal structures of the enzyme HIV-1 pro...
Human immunodeficiency virus type 1 (HIV-1) protease processes and cleaves the Gag and Gag-Pol polyp...
HIV-1 protease (PR) permits viral maturation by processing the Gag and Gag-Pro-Pol polyproteins. Tho...
A recent crystal structure of HIV‐1 protease (HIVp) was the first to experimentally observe a ligand...
We present the discovery of low molecular weight inhibitors of human immunodeficiency virus 1 (HIV-1...
Motivation: HIV-1 protease is a key drug target due to its role in the life cycle of the HIV-1 virus...
AbstractThe crystal structure of HIV-1 protease with an inhibitor has been compared with the structu...
Human immunodeficiency virus type 1 (HIV-1) protease (PR) permits viral maturation by processing the...