Efficient coupling of cellular energy production to metabolic demand is crucial to maintain organismal homeostasis. Here, we report that the mitochondrial Sirtuin Sirt4 regulates mitochondrial ATP homeostasis. We find that Sirt4 affects mitochondrial unco
SummarySirtuins (SIRTs) are critical enzymes that govern genome regulation, metabolism, and aging. D...
International audienceRecently the function of the sirtuin family, named after their homology to the...
The quality of mitochondria is a key determinant of mitochondrial ATP production and reactive oxygen...
The yeast silent information regulator 2 (Sir2)-like group of enzymes (sirtuins) are nicotinamide ad...
SIRT3, SIRT4, and SIRT5 are mitochondrial deacylases that impact multiple facets of energy metabolis...
SIRT3, SIRT4, and SIRT5 are mitochondrial deacylases that impact multiple facets of energy metabolis...
Sirtuins are highly conserved NAD+-dependent protein deacetylases and/or ADP-ribosyltransferases tha...
Sirtuins are a family of protein deacetylases, deacylases, and ADP-ribosyltransferases that regulate...
Sirtuin 5 (SIRT5) is a member of the NAD+-dependent sirtuin family of protein deacylase that catalyz...
Sirtuin 5 (SIRT5) is a member of the NAD+-dependent sirtuin family of protein deacylase that catalyz...
Sirtuins are homologues of the yeast transcriptional repressor Sir2p and are conserved from bacteria...
Sirtuins have emerged in recent years as critical regulators of metabolism, influencing numerous fac...
Lipid metabolism is tightly controlled by the nutritional state of the organism. Nutrient-rich condi...
SIRT3, SIRT4, and SIRT5 are mitochondrial deacylases that impact multiple facets of energy metabolis...
Sirtuins comprise a family of nicotinamide adenine dinucleotide (NAD+)-dependent lysine deacylases t...
SummarySirtuins (SIRTs) are critical enzymes that govern genome regulation, metabolism, and aging. D...
International audienceRecently the function of the sirtuin family, named after their homology to the...
The quality of mitochondria is a key determinant of mitochondrial ATP production and reactive oxygen...
The yeast silent information regulator 2 (Sir2)-like group of enzymes (sirtuins) are nicotinamide ad...
SIRT3, SIRT4, and SIRT5 are mitochondrial deacylases that impact multiple facets of energy metabolis...
SIRT3, SIRT4, and SIRT5 are mitochondrial deacylases that impact multiple facets of energy metabolis...
Sirtuins are highly conserved NAD+-dependent protein deacetylases and/or ADP-ribosyltransferases tha...
Sirtuins are a family of protein deacetylases, deacylases, and ADP-ribosyltransferases that regulate...
Sirtuin 5 (SIRT5) is a member of the NAD+-dependent sirtuin family of protein deacylase that catalyz...
Sirtuin 5 (SIRT5) is a member of the NAD+-dependent sirtuin family of protein deacylase that catalyz...
Sirtuins are homologues of the yeast transcriptional repressor Sir2p and are conserved from bacteria...
Sirtuins have emerged in recent years as critical regulators of metabolism, influencing numerous fac...
Lipid metabolism is tightly controlled by the nutritional state of the organism. Nutrient-rich condi...
SIRT3, SIRT4, and SIRT5 are mitochondrial deacylases that impact multiple facets of energy metabolis...
Sirtuins comprise a family of nicotinamide adenine dinucleotide (NAD+)-dependent lysine deacylases t...
SummarySirtuins (SIRTs) are critical enzymes that govern genome regulation, metabolism, and aging. D...
International audienceRecently the function of the sirtuin family, named after their homology to the...
The quality of mitochondria is a key determinant of mitochondrial ATP production and reactive oxygen...