The adult mammalian heart possesses little regenerative potential following injury. Fibrosis due to activation of cardiac fibroblasts impedes cardiac regeneration and contributes to loss of contractile function, pathological remodelling and susceptibilit
Cardiac development is characterized by a complex interplay of chemical, mechanical, and electrical ...
The limited ability of mammalian adult cardiomyocytes to proliferate following an injury to the hear...
Ischemic cell death during a myocardial infarction leads to a multiphase reparative response in whic...
Cardiac regeneration is a homeostatic cardiogenic process by which the sections of malfunctioning ad...
Abstract Inflammatory and fibrotic responses to myocardial damage are essential for cardiac repair; ...
The relative resistance of fibroblasts to hypoxia and their remarkable adaptive plasticity in respon...
Adult humans fail to regenerate their hearts following injury, and this failure to regenerate myocar...
In the adult, tissue repair after injury is generally compromised by fibrosis, which maintains tissu...
Structural changes in the developing heart may influence the limited regenerative capacity of the ad...
Coronary heart disease is a leading cause of mortality and morbidity. Those that survive acute myoca...
Heart disease affects millions worldwide and is a progressive condition involving loss of cardiomyoc...
The human adult heart lacks a robust endogenous repair mechanism to fully restore cardiac function a...
Despite considerable efforts carried out to develop stem/progenitor cell-based technologies aiming a...
Tese de mestrado, Biologia Evolutiva e do Desenvolvimento, Universidade de Lisboa, Faculdade de Ciên...
Myocardial infarction leads to irreversible cell loss and scar forma-tion, which result in impaired ...
Cardiac development is characterized by a complex interplay of chemical, mechanical, and electrical ...
The limited ability of mammalian adult cardiomyocytes to proliferate following an injury to the hear...
Ischemic cell death during a myocardial infarction leads to a multiphase reparative response in whic...
Cardiac regeneration is a homeostatic cardiogenic process by which the sections of malfunctioning ad...
Abstract Inflammatory and fibrotic responses to myocardial damage are essential for cardiac repair; ...
The relative resistance of fibroblasts to hypoxia and their remarkable adaptive plasticity in respon...
Adult humans fail to regenerate their hearts following injury, and this failure to regenerate myocar...
In the adult, tissue repair after injury is generally compromised by fibrosis, which maintains tissu...
Structural changes in the developing heart may influence the limited regenerative capacity of the ad...
Coronary heart disease is a leading cause of mortality and morbidity. Those that survive acute myoca...
Heart disease affects millions worldwide and is a progressive condition involving loss of cardiomyoc...
The human adult heart lacks a robust endogenous repair mechanism to fully restore cardiac function a...
Despite considerable efforts carried out to develop stem/progenitor cell-based technologies aiming a...
Tese de mestrado, Biologia Evolutiva e do Desenvolvimento, Universidade de Lisboa, Faculdade de Ciên...
Myocardial infarction leads to irreversible cell loss and scar forma-tion, which result in impaired ...
Cardiac development is characterized by a complex interplay of chemical, mechanical, and electrical ...
The limited ability of mammalian adult cardiomyocytes to proliferate following an injury to the hear...
Ischemic cell death during a myocardial infarction leads to a multiphase reparative response in whic...