Relaxin is a naturally occurring human peptide initially identified as a reproductive hormone. More recently, relaxin has been shown to play a key role in the maternal hemodynamic and renal adjustments that accommodate pregnancy. An understanding of these physiologic effects has led to the evaluation of relaxin as a pharmacologic agent for the treatment of patients with acute heart failure. Preliminary results have been encouraging. In addition, the other known biologic properties of relaxin, including anti-inflammatory effects, extracellular matrix remodeling effects, and angiogenic and anti-ischemic effects, all may play a role in potential benefits of relaxin therapy. Ongoing, large-scale clinical testing will provide additional insights...
Background Most patients admitted for acute heart failure have normal or increase blood pressure. Re...
Fibrosis refers to the hardening or scarring of tissues that usually results from aberrant wound hea...
Recent advances in our understanding of the hormone relaxin, and the discovery of its specific recep...
Relaxin is a naturally occurring human peptide initially identified as a reproductive hormone. More ...
Relaxin is a naturally occurring peptide hormone that plays a central role in the hemodynamic and re...
First published February 7, 2018The peptide hormone relaxin has numerous roles both within and indep...
Abstract: Human relaxin-2 (hereafter simply defined as “relaxin”) is a 6-kDa peptidic hormone best k...
Relaxin (a peptide hormone) has emerged as a cardioprotective agent and plays a vital role in normal...
Daniele BaniDepartment of Anatomy, Histology and Forensic Medicine, Sect. Histology, University of F...
Background Acute heart failure (AHF) remains a major public health burden with a high prevalence and...
Published: 15 May 2018Cardiovascular complications are the major cause of mortality in patients with...
Over the past few decades, research on the peptide hormone, relaxin, has significantly improved our ...
Fibrosis (organ scarring) is a hallmark of many forms of cardiovascular and renal disease, and cause...
Relaxin is a peptide hormone emanating from the corpus luteum of the ovary which circulates during p...
Cardiovascular complications are the major cause of mortality in patients with diabetes. This is clo...
Background Most patients admitted for acute heart failure have normal or increase blood pressure. Re...
Fibrosis refers to the hardening or scarring of tissues that usually results from aberrant wound hea...
Recent advances in our understanding of the hormone relaxin, and the discovery of its specific recep...
Relaxin is a naturally occurring human peptide initially identified as a reproductive hormone. More ...
Relaxin is a naturally occurring peptide hormone that plays a central role in the hemodynamic and re...
First published February 7, 2018The peptide hormone relaxin has numerous roles both within and indep...
Abstract: Human relaxin-2 (hereafter simply defined as “relaxin”) is a 6-kDa peptidic hormone best k...
Relaxin (a peptide hormone) has emerged as a cardioprotective agent and plays a vital role in normal...
Daniele BaniDepartment of Anatomy, Histology and Forensic Medicine, Sect. Histology, University of F...
Background Acute heart failure (AHF) remains a major public health burden with a high prevalence and...
Published: 15 May 2018Cardiovascular complications are the major cause of mortality in patients with...
Over the past few decades, research on the peptide hormone, relaxin, has significantly improved our ...
Fibrosis (organ scarring) is a hallmark of many forms of cardiovascular and renal disease, and cause...
Relaxin is a peptide hormone emanating from the corpus luteum of the ovary which circulates during p...
Cardiovascular complications are the major cause of mortality in patients with diabetes. This is clo...
Background Most patients admitted for acute heart failure have normal or increase blood pressure. Re...
Fibrosis refers to the hardening or scarring of tissues that usually results from aberrant wound hea...
Recent advances in our understanding of the hormone relaxin, and the discovery of its specific recep...