The U.S. Department of Agriculture, Animal and Plant Health Inspection Service (APHIS) has two federal (Section 3) vertebrate pesticide registrations with the U.S. Environmental Protection Agency (EPA) for gas cartridges to control damage to American agricultural resources and reduce threats to public health and safety. The gas cartridges are pyro-fumigant devices that produce primarily carbon monoxide when ignited. In sealed burrows or dens, carbon monoxide is highly toxic when inhaled, leading to tissue hypoxia. Carbon monoxide is recommended by the American Veterinary Medicine Association's panel for euthanatizing animals because it quickly induces unconsciousness without pain and with minimal discernible discomfort. APHIS's gas cartridg...