Add to ORKGThe class III PI 3-kinase, VPS34 forms distinct complexes essential for cargo sorting and membrane trafficking in endocytosis as well as for autophagosome nucleation and maturation. We used integrative structural biology approach to provide insights into the conformational dynamics of the complex and mechanisms that regulate VPS34 activity at the membrane
The lipid phosphatidylinositol-3-phosphate (PI3P) is a regulator of two fundamental but distinct cel...
Phosphatidylinositol 3-phosphate (PI(3)P) serves important functions in endocytosis, phagocytosis, a...
The class II phosphoinositide 3-kinase PI3K-C2α is an enzyme that phosphorylates phosphatidylinositi...
The class III PI 3-kinase, VPS34 forms distinct complexes essential for cargo sorting and membrane t...
The class III phosphatidylinositol 3-kinase complex I (PI3KC3-C1) is required for the initiation of ...
The lipid kinase VPS34 orchestrates diverse processes, including autophagy, endocytic sorting, phago...
Vps34 is the primordial member of the PI3 kinase family involved in vesicular trafficking, nutrient ...
The class III phosphoinositide 3-kinase VPS34 regulates autophagosome formation. Three groups have d...
Phosphatidylinositol 3-kinase Vps34 complexes regulate intracellular membrane trafficking in endocyt...
The class III phosphatidylinositol 3-kinase complex I (PI3KC3-C1) that functions in early autophagy ...
The lipid phosphatidylinositol-3-phosphate (PI3P) is a regulator of two fundamental but distinct cel...
Phosphatidylinositol 3-phosphate (PI(3)P) serves important functions in endocytosis, phagocytosis, a...
The class II phosphoinositide 3-kinase PI3K-C2α is an enzyme that phosphorylates phosphatidylinositi...
The class III PI 3-kinase, VPS34 forms distinct complexes essential for cargo sorting and membrane t...
The class III phosphatidylinositol 3-kinase complex I (PI3KC3-C1) is required for the initiation of ...
The lipid kinase VPS34 orchestrates diverse processes, including autophagy, endocytic sorting, phago...
Vps34 is the primordial member of the PI3 kinase family involved in vesicular trafficking, nutrient ...
The class III phosphoinositide 3-kinase VPS34 regulates autophagosome formation. Three groups have d...
Phosphatidylinositol 3-kinase Vps34 complexes regulate intracellular membrane trafficking in endocyt...
The class III phosphatidylinositol 3-kinase complex I (PI3KC3-C1) that functions in early autophagy ...
The lipid phosphatidylinositol-3-phosphate (PI3P) is a regulator of two fundamental but distinct cel...
Phosphatidylinositol 3-phosphate (PI(3)P) serves important functions in endocytosis, phagocytosis, a...
The class II phosphoinositide 3-kinase PI3K-C2α is an enzyme that phosphorylates phosphatidylinositi...