Mitosis is a highly regulated set of events that culminates in cell division and the segregation of an equal amount of genetic material to two daughter cells. XPMC2H is a protein that has been implicated in cell division, but its exact role is uncertain. It is linked to suppressing tumors by correcting mitotic defects, regulating transcription, and modifying ribosomes. The Spin3 protein is associated with mitotic spindle organization and stability; however, its physiological function is also unknown. To clarify the roles of XPMC2H and Spin3 in cell division, their complexes were purified so that their protein interactors could be identified. In addition, the cellular consequences of modulating the protein levels of XPMC2H and Spin3 were ana...
Mitosis is a highly regulated process characterized by dramatic and coordinated morphological chang...
Progression through the phases of the cell cycle (G1, S, G2, and mitosis) is largely driven by the c...
Contains fulltext : 110087.pdf (publisher's version ) (Open Access)Most human tumo...
During mitosis, the vertebrate cell nucleus undergoes profound changes in architecture. At the onset...
Contains fulltext : 81260.pdf (publisher's version ) (Open Access)BACKGROUND: Prev...
Proliferation of mammalian cells requires the coordinated function of many proteins to accurately di...
Cell division is fundamental to multicellular organisms, and understanding the molecular basis remai...
Mutations in the WDR62 gene cause primary microcephaly, a pathological condition often associated wi...
Cell division is crucial for all organisms. Somatic cell division relays on the separation of the ge...
<div><p>The mitotic spindle is an essential molecular machine involved in cell division, whose compo...
Contains fulltext : 87811.pdf (publisher's version ) (Open Access)BACKGROUND: Alth...
During mitotic cell division, the genetic material packed into chromosomes is divided equally betwee...
ABSTRACT Class IA phosphoinositide 3-kinases (PI3K) are enzymes composed of a p85 regu-latory and a ...
The discovery of novel cell division proteins is important to further understand the basic mechanism...
Mitotic spindle assembly is a highly complex and specifically orchestrated event that occurs once pe...
Mitosis is a highly regulated process characterized by dramatic and coordinated morphological chang...
Progression through the phases of the cell cycle (G1, S, G2, and mitosis) is largely driven by the c...
Contains fulltext : 110087.pdf (publisher's version ) (Open Access)Most human tumo...
During mitosis, the vertebrate cell nucleus undergoes profound changes in architecture. At the onset...
Contains fulltext : 81260.pdf (publisher's version ) (Open Access)BACKGROUND: Prev...
Proliferation of mammalian cells requires the coordinated function of many proteins to accurately di...
Cell division is fundamental to multicellular organisms, and understanding the molecular basis remai...
Mutations in the WDR62 gene cause primary microcephaly, a pathological condition often associated wi...
Cell division is crucial for all organisms. Somatic cell division relays on the separation of the ge...
<div><p>The mitotic spindle is an essential molecular machine involved in cell division, whose compo...
Contains fulltext : 87811.pdf (publisher's version ) (Open Access)BACKGROUND: Alth...
During mitotic cell division, the genetic material packed into chromosomes is divided equally betwee...
ABSTRACT Class IA phosphoinositide 3-kinases (PI3K) are enzymes composed of a p85 regu-latory and a ...
The discovery of novel cell division proteins is important to further understand the basic mechanism...
Mitotic spindle assembly is a highly complex and specifically orchestrated event that occurs once pe...
Mitosis is a highly regulated process characterized by dramatic and coordinated morphological chang...
Progression through the phases of the cell cycle (G1, S, G2, and mitosis) is largely driven by the c...
Contains fulltext : 110087.pdf (publisher's version ) (Open Access)Most human tumo...