Add to ORKGIn this issue of JEM, Boucher et al. (https://doi.org/10.1084/jem.20172222) report isolation of active caspase-1 from macrophages after inflammasome activation. Surprisingly, they find that caspase-1 is quickly inactivated upon autoproteolytic processing
© 2017 Elsevier Ltd Autophagy is a ubiquitous cellular mechanism for the targeted lysosomal degradat...
Caspase-1, formerly known as interleukin (IL)-1-converting enzyme is best established as the proteas...
Phagocytosis of PAMPs, DAMPs and certain dying cells can activate the inflammasome pathway in macrop...
In this issue of JEM, Boucher et al. (https://doi.org/10.1084/jem.20172222) report isolation of acti...
Host-protective caspase-1 activity must be tightly regulated to prevent pathology, but mechanisms co...
SummaryActivation of the cysteine protease Caspase-1 is a key event in the innate immune response to...
Activation of the cysteine protease Caspase-1 is a key event in the innate immune response to infect...
Activation of the inflammatory cysteine protease caspase-1 in inflammasome complexes plays a critica...
Caspase-1 plays a fundamental role in innate immunity and in several important inflammatory diseases...
The caspase-1 protease is a core component of multiprotein inflammasome complexes, which play a crit...
Contains fulltext : 98006.pdf (publisher's version ) (Closed access)Interleukin-1b...
Canonical inflammasomes are multiprotein complexes that can activate both caspase-1 and caspase-8. C...
THESIS 11066Caspases are a group of proteolytic enzymes involved in the co-ordination of cellular pr...
Inflammation is the bodies first response to defend itself against foreign pathogens and damage. Cel...
Inflammasomes are cytosolic multiprotein platforms assembled in response to invading pathogens and o...
© 2017 Elsevier Ltd Autophagy is a ubiquitous cellular mechanism for the targeted lysosomal degradat...
Caspase-1, formerly known as interleukin (IL)-1-converting enzyme is best established as the proteas...
Phagocytosis of PAMPs, DAMPs and certain dying cells can activate the inflammasome pathway in macrop...
In this issue of JEM, Boucher et al. (https://doi.org/10.1084/jem.20172222) report isolation of acti...
Host-protective caspase-1 activity must be tightly regulated to prevent pathology, but mechanisms co...
SummaryActivation of the cysteine protease Caspase-1 is a key event in the innate immune response to...
Activation of the cysteine protease Caspase-1 is a key event in the innate immune response to infect...
Activation of the inflammatory cysteine protease caspase-1 in inflammasome complexes plays a critica...
Caspase-1 plays a fundamental role in innate immunity and in several important inflammatory diseases...
The caspase-1 protease is a core component of multiprotein inflammasome complexes, which play a crit...
Contains fulltext : 98006.pdf (publisher's version ) (Closed access)Interleukin-1b...
Canonical inflammasomes are multiprotein complexes that can activate both caspase-1 and caspase-8. C...
THESIS 11066Caspases are a group of proteolytic enzymes involved in the co-ordination of cellular pr...
Inflammation is the bodies first response to defend itself against foreign pathogens and damage. Cel...
Inflammasomes are cytosolic multiprotein platforms assembled in response to invading pathogens and o...
© 2017 Elsevier Ltd Autophagy is a ubiquitous cellular mechanism for the targeted lysosomal degradat...
Caspase-1, formerly known as interleukin (IL)-1-converting enzyme is best established as the proteas...
Phagocytosis of PAMPs, DAMPs and certain dying cells can activate the inflammasome pathway in macrop...