Important requirements for exogenous dyes or contrast agents in magnetic resonance imaging (MRI) include an effective concentration of paramagnetic or superparamagnetic ions at the target to be imaged. We report the concise synthesis and characterization of several new enantiopure bifunctional derivatives of (α(1)R,α(4)R,α(7)R,α(10)R)-α(1),α(4),α(7),α(10)-tetramethyl-1,4,7,10-tetraazacyclododecane-1,4,7,10-tetraacetic acid (DOTMA) (and their 1,4,7,10-tetraazacyclododecane-1,4,7,10-tetraacetic acid (DOTA) analogues as controls) that can be covalently attached to a contrast agent delivery system using either click or peptide coupling chemistry. Gd complexes of these derivatives can be attached to delivery systems while maintaining optimal wat...
The bifunctional chelator S-2-(4-isothiocyanatobenzyl)-1,4,7,10-tetraazacyclododecane-N,N′,N″,N‴-1,4...
Smart MR contrast agents exhibit modulation of their relaxivity by specific physiological or biochem...
Molecular imaging requires the specific accumulation of contrast agents at the target. To exploit th...
Important requirements for exogenous dyes or contrast agents in magnetic resonance imaging (MRI) inc...
ABSTRACT: Important requirements for exogenous dyes or contrast agents in magnetic resonance imaging...
Important requirements for exogenous dyes or contrast agents in magnetic resonance imaging (MRI) inc...
Important requirements for exogenous dyes or contrast agents in magnetic resonance imaging (MRI) inc...
Important requirements for exogenous dyes or contrast agents in magnetic resonance imaging (MRI) inc...
Molecular imaging requires the specific accumulation of contrast agents at the target. To exploit th...
One major challenge in noninvasive mapping of various molecular targets is their inherently low in v...
A new bimodal and multivalent dendritic contrast agent (CA) that targets the protein avidin was prep...
Smart MR contrast agents are chelated paramagnetic molecules, whose relaxivity changes as a function...
The bifunctional chelator S-2-(4-isothiocyanatobenzyl)-1,4,7,10-tetraazacyclododecane-N,N′,N″,N‴-1,4...
Smart MR contrast agents are chelated paramagnetic molecules, whose relaxivity changes as a function...
Molecular imaging requires the specific accumulation of contrast agents at the target. To exploit th...
The bifunctional chelator S-2-(4-isothiocyanatobenzyl)-1,4,7,10-tetraazacyclododecane-N,N′,N″,N‴-1,4...
Smart MR contrast agents exhibit modulation of their relaxivity by specific physiological or biochem...
Molecular imaging requires the specific accumulation of contrast agents at the target. To exploit th...
Important requirements for exogenous dyes or contrast agents in magnetic resonance imaging (MRI) inc...
ABSTRACT: Important requirements for exogenous dyes or contrast agents in magnetic resonance imaging...
Important requirements for exogenous dyes or contrast agents in magnetic resonance imaging (MRI) inc...
Important requirements for exogenous dyes or contrast agents in magnetic resonance imaging (MRI) inc...
Important requirements for exogenous dyes or contrast agents in magnetic resonance imaging (MRI) inc...
Molecular imaging requires the specific accumulation of contrast agents at the target. To exploit th...
One major challenge in noninvasive mapping of various molecular targets is their inherently low in v...
A new bimodal and multivalent dendritic contrast agent (CA) that targets the protein avidin was prep...
Smart MR contrast agents are chelated paramagnetic molecules, whose relaxivity changes as a function...
The bifunctional chelator S-2-(4-isothiocyanatobenzyl)-1,4,7,10-tetraazacyclododecane-N,N′,N″,N‴-1,4...
Smart MR contrast agents are chelated paramagnetic molecules, whose relaxivity changes as a function...
Molecular imaging requires the specific accumulation of contrast agents at the target. To exploit th...
The bifunctional chelator S-2-(4-isothiocyanatobenzyl)-1,4,7,10-tetraazacyclododecane-N,N′,N″,N‴-1,4...
Smart MR contrast agents exhibit modulation of their relaxivity by specific physiological or biochem...
Molecular imaging requires the specific accumulation of contrast agents at the target. To exploit th...