Add to ORKGReliable molecular diagnostics, which detect specific mutations associated with drug resistance, are promising technologies for the rapid identification and monitoring of drug resistance in Mycobacterium tuberculosis isolates. Pyrosequencing (PSQ) has the ability to detect mutations associated with first- and second-line anti-tuberculosis (TB) drugs, with the additional advantage of being rapidly adaptable for the identification of new mutations. The aim of this project was to evaluate the performance of PSQ in predicting phenotypic drug resistance in multidrug- and extensively drug-resistant tuberculosis (M/XDR-TB) clinical isolates from India, South Africa, Moldova, and the Philippines. A total of 187 archived isolates were run through a ...
A multicenter study was conducted with the objective to evaluate a reverse line blot (RLB) assay to ...
AbstractIntroductionThe four basic or “first-line” TB drugs are Isoniazid, Rifampicin, Pyrazinamide ...
Developing a fast, inexpensive, and specific test that reflects the mutations present in Mycobacteri...
Reliable molecular diagnostics, which detect specific mutations associated with drug resistance, are...
Conventional phenotypic drug susceptibility testing (DST) methods forMycobacterium tuberculosis are ...
Conventional phenotypic drug susceptibility testing (DST) methods forMycobacterium tuberculosis are ...
BackgroundRapid molecular diagnostics, with their ability to quickly identify genetic mutations asso...
Having an accurate and timely diagnostics tool for infectious diseases is important for clinician...
Molecular diagnostic methods based on the detection of mutations conferring drug resistance are prom...
AbstractBackgroundRapid and accurate techniques are always welcomed for the detection of resistant s...
Background: Multidrug and extensively drug-resistant tuberculosis (M/XDR-TB) pose major threats to g...
Despite the WHO's call for universal drug susceptibility testing for all patients being evaluated fo...
Past genotypic studies of Mycobacterium tuberculosis may have incorrectly estimated the importance o...
AbstractIn this study, a pyrosequencing method for monitoring two genes related to isoniazid (INH)-r...
Multi- drug resistant tuberculosis continues to be a serious problem, particularly among some develo...
A multicenter study was conducted with the objective to evaluate a reverse line blot (RLB) assay to ...
AbstractIntroductionThe four basic or “first-line” TB drugs are Isoniazid, Rifampicin, Pyrazinamide ...
Developing a fast, inexpensive, and specific test that reflects the mutations present in Mycobacteri...
Reliable molecular diagnostics, which detect specific mutations associated with drug resistance, are...
Conventional phenotypic drug susceptibility testing (DST) methods forMycobacterium tuberculosis are ...
Conventional phenotypic drug susceptibility testing (DST) methods forMycobacterium tuberculosis are ...
BackgroundRapid molecular diagnostics, with their ability to quickly identify genetic mutations asso...
Having an accurate and timely diagnostics tool for infectious diseases is important for clinician...
Molecular diagnostic methods based on the detection of mutations conferring drug resistance are prom...
AbstractBackgroundRapid and accurate techniques are always welcomed for the detection of resistant s...
Background: Multidrug and extensively drug-resistant tuberculosis (M/XDR-TB) pose major threats to g...
Despite the WHO's call for universal drug susceptibility testing for all patients being evaluated fo...
Past genotypic studies of Mycobacterium tuberculosis may have incorrectly estimated the importance o...
AbstractIn this study, a pyrosequencing method for monitoring two genes related to isoniazid (INH)-r...
Multi- drug resistant tuberculosis continues to be a serious problem, particularly among some develo...
A multicenter study was conducted with the objective to evaluate a reverse line blot (RLB) assay to ...
AbstractIntroductionThe four basic or “first-line” TB drugs are Isoniazid, Rifampicin, Pyrazinamide ...
Developing a fast, inexpensive, and specific test that reflects the mutations present in Mycobacteri...