Add to ORKGFragile X syndrome (FXS) is the most common genetic cause of intellectual disability and the most common single-gene cause of autism. It is caused by mutations on the fragile X mental retardation gene (FMR1) and lack of fragile X mental retardation protein, which in turn, leads to decreased inhibition of translation of many synaptic proteins. The metabotropic glutamate receptor (mGluR) hypothesis states that the neurological deficits in individuals with FXS are due mainly to downstream consequences of overstimulation of the mGluR pathway. The main efforts have focused on mGluR5 targeted treatments; however, investigation on the gamma-aminobutyric acid (GABA) system and its potential as a targeted treatment is less emphasized. The fragile X ...
Research on animal models of fragile X syndrome suggests that STX209, a γ-aminobutyric acid type B (...
Background: Fragile X syndrome (FXS), the most common single-gene cause of intellectual disability a...
Fragile X syndrome (FXS), the most common monogenetic cause of intellectual disability and autism sp...
Fragile X syndrome (FXS) is the most common genetic cause of intellectual disability and the most co...
Fragile X syndrome (FXS) is caused by a lack of the fragile X mental retardation protein (FMRP); FMR...
Fragile X spectrum disorder (FXSD) includes: fragile X syndrome (FXS), fragile X-associated tremor a...
Molecular and electrophysiological studies have provided evidence for a general downregulation of th...
Fragile X syndrome (FXS) is the most common monogenetic cause of intellectual disability and autism....
Fragile X syndrome (FXS) is the most common monogenetic cause of intellectual disability and autism....
Neurodevelopmental disorders such as fragile X syndrome (FXS) result in lifelong cognitive and behav...
Fragile X syndrome (FXS) is considered the leading inherited cause of intellectual disability and au...
International audienceFragile X syndrome, the main cause of inherited mental retardation, is caused ...
Neurodevelopmental disorders such as fragile X syndrome (FXS) result in lifelong cognitive and behav...
Fragile X syndrome is the most common monogenetic form of intellectual disability and is a leading c...
Abstract Fragile X syndrome (FXS) is the most common identifiable genetic cause of intellectual disa...
Research on animal models of fragile X syndrome suggests that STX209, a γ-aminobutyric acid type B (...
Background: Fragile X syndrome (FXS), the most common single-gene cause of intellectual disability a...
Fragile X syndrome (FXS), the most common monogenetic cause of intellectual disability and autism sp...
Fragile X syndrome (FXS) is the most common genetic cause of intellectual disability and the most co...
Fragile X syndrome (FXS) is caused by a lack of the fragile X mental retardation protein (FMRP); FMR...
Fragile X spectrum disorder (FXSD) includes: fragile X syndrome (FXS), fragile X-associated tremor a...
Molecular and electrophysiological studies have provided evidence for a general downregulation of th...
Fragile X syndrome (FXS) is the most common monogenetic cause of intellectual disability and autism....
Fragile X syndrome (FXS) is the most common monogenetic cause of intellectual disability and autism....
Neurodevelopmental disorders such as fragile X syndrome (FXS) result in lifelong cognitive and behav...
Fragile X syndrome (FXS) is considered the leading inherited cause of intellectual disability and au...
International audienceFragile X syndrome, the main cause of inherited mental retardation, is caused ...
Neurodevelopmental disorders such as fragile X syndrome (FXS) result in lifelong cognitive and behav...
Fragile X syndrome is the most common monogenetic form of intellectual disability and is a leading c...
Abstract Fragile X syndrome (FXS) is the most common identifiable genetic cause of intellectual disa...
Research on animal models of fragile X syndrome suggests that STX209, a γ-aminobutyric acid type B (...
Background: Fragile X syndrome (FXS), the most common single-gene cause of intellectual disability a...
Fragile X syndrome (FXS), the most common monogenetic cause of intellectual disability and autism sp...