Chronic kidney disease results in disruption of the intestinal epithelial barrier as well as profound changes in the gut microbial flora. These events are largely mediated by (1) heavy influx of circulating urea to the gut lumen and (2) dietary restrictions of foods containing high fiber (such as fruits and vegetable) and symbiotic organisms (such as yogurt and cheese) imposed to mitigate hyperkalemia and hyperphosphatemia. Collectively, these factors promote systemic inflammation and cardiovascular morbidity by mediating microbial dysbiosis, disruption of the intestinal epithelial barrier, and translocation of endotoxin, bacterial fragments, and uremic toxins across the "leaky gut" into the bloodstream. Strategies aimed at increasing dieta...
International audienceInflammation is a multifactorial phenotype that in chronic kidney disease is a...
Recent studies have found a relationship between the kidney and the intestinal microbiome, called th...
Recent studies have found a relationship between the kidney and the intestinal microbiome, called th...
In the past, little attention had been paid to the intestine and its microbial flora as a potential ...
Chronic inflammation is a non-traditional risk factor for cardiovascular mortality in the chronic ki...
Recent studies have highlighted the close relationship between the kidney and the gastrointestinal (...
In chronic kidney disease (CKD), influx of urea and other retained toxins exerts a change in the gut...
During chronic kidney disease (CKD), typical alterations in the gut microbiota are observed. The kid...
International audienceThe normal intestinal microbiota plays a major role in the maintenance of heal...
Chronic kidney disease (CKD) has been shown to result in profound changes in the composition and fun...
Environmental changes can induce diversity shifts within ecosystems that affect interactions between...
Chronic kidney disease (CKD) is generally progressive and irreversible, structural or functional ren...
The gut microbiota consists of trillions of microorganisms, fulfilling important roles in metabolism...
Chronic kidney disease (CKD) is associated with systemic inflammation. The latter accelerates comorb...
Chronic kidney disease (CKD) results in systemic inflammation and oxidative stress which play a cent...
International audienceInflammation is a multifactorial phenotype that in chronic kidney disease is a...
Recent studies have found a relationship between the kidney and the intestinal microbiome, called th...
Recent studies have found a relationship between the kidney and the intestinal microbiome, called th...
In the past, little attention had been paid to the intestine and its microbial flora as a potential ...
Chronic inflammation is a non-traditional risk factor for cardiovascular mortality in the chronic ki...
Recent studies have highlighted the close relationship between the kidney and the gastrointestinal (...
In chronic kidney disease (CKD), influx of urea and other retained toxins exerts a change in the gut...
During chronic kidney disease (CKD), typical alterations in the gut microbiota are observed. The kid...
International audienceThe normal intestinal microbiota plays a major role in the maintenance of heal...
Chronic kidney disease (CKD) has been shown to result in profound changes in the composition and fun...
Environmental changes can induce diversity shifts within ecosystems that affect interactions between...
Chronic kidney disease (CKD) is generally progressive and irreversible, structural or functional ren...
The gut microbiota consists of trillions of microorganisms, fulfilling important roles in metabolism...
Chronic kidney disease (CKD) is associated with systemic inflammation. The latter accelerates comorb...
Chronic kidney disease (CKD) results in systemic inflammation and oxidative stress which play a cent...
International audienceInflammation is a multifactorial phenotype that in chronic kidney disease is a...
Recent studies have found a relationship between the kidney and the intestinal microbiome, called th...
Recent studies have found a relationship between the kidney and the intestinal microbiome, called th...