Add to ORKGAimTo examine variation in child DNA methylation to assess its potential as a pathway for effects of childhood social adversity on health across the life course.Materials & methodsIn a diverse, prospective community sample of 178 kindergarten children, associations between three types of social experience and DNA methylation within buccal epithelial cells later in childhood were examined.ResultsFamily income, parental education and family psychosocial adversity each associated with increased or decreased DNA methylation (488, 354 and 102 sites, respectively) within a unique set of genomic CpG sites. Gene ontology analyses pointed to genes serving immune and developmental regulation functions.ConclusionFindings provided support for DNA m...
Lasting effects of adversity, such as exposure to childhood adversity (CA) on disease risk, may be e...
[[abstract]]Prenatal development and early childhood are critical periods for establishing the tissu...
DNA methylation has been proposed as an epigenetic mechanism by which early-life experiences become ...
AimTo examine variation in child DNA methylation to assess its potential as a pathway for effects of...
Childhood socioeconomic position (SEP) is a major determinant of health and well-being across the en...
Many early experiences and exposures are known to cause health disparities later in life, suggesting...
A growing body of research has documented associations between adverse childhood environments and DN...
Childhood maltreatment (CM) is an established major risk factor for a number of negative health outc...
BACKGROUND: DNA methylation has been found to associate with disease, aging and environmental exposu...
Low prosocial behavior in childhood has been consistently linked to later psychopathology, with evid...
BACKGROUND: DNA methylation has been found to associate with disease, aging and envi...
Early social deprivation (i.e., an insufficiency or lack of parental care) has been identified as a ...
Childhood adversity is a potent determinant of health across development and is associated with alte...
Early social deprivation (i.e., an insufficiency or lack of parental care) has been identified as a ...
Low prosocial behavior in childhood has been consistently linked to later psychopathology, with evid...
Lasting effects of adversity, such as exposure to childhood adversity (CA) on disease risk, may be e...
[[abstract]]Prenatal development and early childhood are critical periods for establishing the tissu...
DNA methylation has been proposed as an epigenetic mechanism by which early-life experiences become ...
AimTo examine variation in child DNA methylation to assess its potential as a pathway for effects of...
Childhood socioeconomic position (SEP) is a major determinant of health and well-being across the en...
Many early experiences and exposures are known to cause health disparities later in life, suggesting...
A growing body of research has documented associations between adverse childhood environments and DN...
Childhood maltreatment (CM) is an established major risk factor for a number of negative health outc...
BACKGROUND: DNA methylation has been found to associate with disease, aging and environmental exposu...
Low prosocial behavior in childhood has been consistently linked to later psychopathology, with evid...
BACKGROUND: DNA methylation has been found to associate with disease, aging and envi...
Early social deprivation (i.e., an insufficiency or lack of parental care) has been identified as a ...
Childhood adversity is a potent determinant of health across development and is associated with alte...
Early social deprivation (i.e., an insufficiency or lack of parental care) has been identified as a ...
Low prosocial behavior in childhood has been consistently linked to later psychopathology, with evid...
Lasting effects of adversity, such as exposure to childhood adversity (CA) on disease risk, may be e...
[[abstract]]Prenatal development and early childhood are critical periods for establishing the tissu...
DNA methylation has been proposed as an epigenetic mechanism by which early-life experiences become ...