Add to ORKGFatty acid amide hydrolase (FAAH), a promising target for the treatment of several central and peripheral nervous system disorders, such as anxiety, pain and hypertension, has an unusual catalytic site, and its mechanism has been uncertain; hybrid quantum mechanics/molecular mechanics (QM/MM) calculations reveal a new mechanism of nucleophile activation (involving a Lys-Ser-Ser catalytic triad), with potentially crucial insights for the design of potent and selective inhibitors
Carbamate and urea derivatives are important classes of fatty acid amide hydrolase (FAAH) inhibitors...
Fatty acid amide hydrolase (FAAH) is a member of the amidase signature family and is responsible for...
Herein, we combined classical molecular dynamics (MD) and quantum mechanical/molecular mechanics (QM...
Fatty acid amide hydrolase (FAAH), a promising target for the treatment of several central and perip...
FAAH (fatty acid amide hydrolase) is a promising target for the treatment of several central nervous...
The Fatty Acid Amide Hydrolase (FAAH) enzyme is a membrane-bound serine hydrolase responsible for th...
The Fatty Acid Amide Hydrolase (FAAH) enzyme is a membrane-bound serine hydrolase responsible for th...
Since its first appearance in 1976, the quantum mechanics/molecular mechanics (QM/MM) approach has m...
none4siThe Fatty Acid Amide Hydrolase (FAAH) enzyme is a membrane-bound serine hydrolase responsible...
The Fatty Acid Amide Hydrolase (FAAH) enzyme is a membrane-bound serine hydrolase responsible for th...
Herein, we combined classical molecular dynamics (MD) and quantum mechanical/molecular mechanics (QM...
Herein, we combined classical molecular dynamics (MD) and quantum mechanical/molecular mechanics (QM...
none5siHerein, we combined classical molecular dynamics (MD) and quantum mechanical/molecular mechan...
Fatty acid amide hydrolase (FAAH) is an enzyme responsible for the deactivating hydrolysis of fatty ...
Carbamate and urea derivatives are important classes of fatty acid amide hydrolase (FAAH) inhibitors...
Carbamate and urea derivatives are important classes of fatty acid amide hydrolase (FAAH) inhibitors...
Fatty acid amide hydrolase (FAAH) is a member of the amidase signature family and is responsible for...
Herein, we combined classical molecular dynamics (MD) and quantum mechanical/molecular mechanics (QM...
Fatty acid amide hydrolase (FAAH), a promising target for the treatment of several central and perip...
FAAH (fatty acid amide hydrolase) is a promising target for the treatment of several central nervous...
The Fatty Acid Amide Hydrolase (FAAH) enzyme is a membrane-bound serine hydrolase responsible for th...
The Fatty Acid Amide Hydrolase (FAAH) enzyme is a membrane-bound serine hydrolase responsible for th...
Since its first appearance in 1976, the quantum mechanics/molecular mechanics (QM/MM) approach has m...
none4siThe Fatty Acid Amide Hydrolase (FAAH) enzyme is a membrane-bound serine hydrolase responsible...
The Fatty Acid Amide Hydrolase (FAAH) enzyme is a membrane-bound serine hydrolase responsible for th...
Herein, we combined classical molecular dynamics (MD) and quantum mechanical/molecular mechanics (QM...
Herein, we combined classical molecular dynamics (MD) and quantum mechanical/molecular mechanics (QM...
none5siHerein, we combined classical molecular dynamics (MD) and quantum mechanical/molecular mechan...
Fatty acid amide hydrolase (FAAH) is an enzyme responsible for the deactivating hydrolysis of fatty ...
Carbamate and urea derivatives are important classes of fatty acid amide hydrolase (FAAH) inhibitors...
Carbamate and urea derivatives are important classes of fatty acid amide hydrolase (FAAH) inhibitors...
Fatty acid amide hydrolase (FAAH) is a member of the amidase signature family and is responsible for...
Herein, we combined classical molecular dynamics (MD) and quantum mechanical/molecular mechanics (QM...