Mechanistic understanding of the endocytosis and intracellular trafficking of nanoparticles is essential for designing smart theranostic carriers. Physico-chemical properties, including size, clustering and surface chemistry of nanoparticles regulate their cellular uptake and transport. Significantly, even single nanoparticles could cluster intracellularly, yet their clustering state and subsequent trafficking are not well understood. Here, we used DNA-decorated gold (fPlas-gold) nanoparticles as a dually emissive fluorescent and plasmonic probe to examine their clustering states and intracellular transport. Evidence from correlative fluorescence and plasmonic imaging shows that endocytosis of fPlas-gold follows multiple pathways. In the ea...
Extracellular vesicles (EVs) are secreted by the vast majority of cells and are being intensively st...
Gold nanoparticles have been researched for many biomedical applications in diagnostics, ther-anosti...
Delivery of short interfering RNAs (siRNAs) remains a key challenge in the development of RNA interf...
Gold nanoparticles have emerged as novel safe and biocompatible tools for manifold applications, inc...
Efficient intracellular delivery of gold nanoparticles (AuNPs) and unraveling the mechanism underlyi...
Previously we have demonstrated surface plasmon enhanced energy transfer between fluorophors and gol...
Due to their small size and related interesting properties, artificial nanoma-terials are utilized f...
Extracellular vesicles (EVs) are secreted by the vast majority of cells and are being intensively st...
Extracellular vesicles (EVs) are secreted by the vast majority of cells and are being intensively st...
Nanoparticles (NPs) are gaining increasing attention for potential application in medicine; conseque...
Directing nanoparticles to the nucleus by attachment of nuclear localization sequences NLS is an a...
Metal nanoclusters (NCs) have emerged as a promising class of fluorescent probes for cellular imagin...
Gold nanoparticles have been researched for many biomedical applications in diagnostics, theranostic...
Aim: We examined cellular uptake mechanisms of fluorescently labeled polymer-coated gold nanoparticl...
Extracellular vesicles (EVs) are secreted by the vast majority of cells and are being intensively st...
Gold nanoparticles have been researched for many biomedical applications in diagnostics, ther-anosti...
Delivery of short interfering RNAs (siRNAs) remains a key challenge in the development of RNA interf...
Gold nanoparticles have emerged as novel safe and biocompatible tools for manifold applications, inc...
Efficient intracellular delivery of gold nanoparticles (AuNPs) and unraveling the mechanism underlyi...
Previously we have demonstrated surface plasmon enhanced energy transfer between fluorophors and gol...
Due to their small size and related interesting properties, artificial nanoma-terials are utilized f...
Extracellular vesicles (EVs) are secreted by the vast majority of cells and are being intensively st...
Extracellular vesicles (EVs) are secreted by the vast majority of cells and are being intensively st...
Nanoparticles (NPs) are gaining increasing attention for potential application in medicine; conseque...
Directing nanoparticles to the nucleus by attachment of nuclear localization sequences NLS is an a...
Metal nanoclusters (NCs) have emerged as a promising class of fluorescent probes for cellular imagin...
Gold nanoparticles have been researched for many biomedical applications in diagnostics, theranostic...
Aim: We examined cellular uptake mechanisms of fluorescently labeled polymer-coated gold nanoparticl...
Extracellular vesicles (EVs) are secreted by the vast majority of cells and are being intensively st...
Gold nanoparticles have been researched for many biomedical applications in diagnostics, ther-anosti...
Delivery of short interfering RNAs (siRNAs) remains a key challenge in the development of RNA interf...