Human brain organoids, generated from pluripotent stem cells, have emerged as a promising technique for modeling early stages of human neurodevelopment in controlled laboratory conditions. Although the applications for disease modeling in a dish have become routine, the use of these brain organoids as evolutionary tools is only now getting momentum. Here, we will review the current state of the art on the use of brain organoids from different species and the molecular and cellular insights generated from these studies. Besides, we will discuss how this model might be beneficial for human health and the limitations and future perspectives of this technology
AbstractThe ability to model human brain development in vitro represents an important step in our st...
Stem cell studies are being currently widely used in neuroscience particularly for degenerative, dev...
Over the past years, brain development has been investigated in rodent models, which were particular...
Human brain organoids, generated from pluripotent stem cells, have emerged as a promising technique ...
Understanding the development and dysfunction of the human brain is a major goal of neurobiology. Mu...
Brain organoids are 3D self-assembled structures composed of hundreds of thousands to millions of ce...
The cerebral cortex forms early in development according to a series of heritable neurodevelopmental...
It is vital for our understanding of human-specific development, behavior, cognition, and disease th...
Over the past years, brain development has been investigated in rodent models, which were particular...
The brain is one of the most complex organs, responsible for the advanced intellectual and cognitive...
Background: Brain organoids are self-organized from human pluripotent stem cells and developed into ...
Human brain development is an intricate process that involves closely timed coordination of cell pro...
The field of developmental neuroscience is benefitting from recent technological advances that allow...
The field of developmental neuroscience is benefitting from recent technological advances that allow...
The past decade has seen an explosion in the identification of genetic causes of neurodevelopmental ...
AbstractThe ability to model human brain development in vitro represents an important step in our st...
Stem cell studies are being currently widely used in neuroscience particularly for degenerative, dev...
Over the past years, brain development has been investigated in rodent models, which were particular...
Human brain organoids, generated from pluripotent stem cells, have emerged as a promising technique ...
Understanding the development and dysfunction of the human brain is a major goal of neurobiology. Mu...
Brain organoids are 3D self-assembled structures composed of hundreds of thousands to millions of ce...
The cerebral cortex forms early in development according to a series of heritable neurodevelopmental...
It is vital for our understanding of human-specific development, behavior, cognition, and disease th...
Over the past years, brain development has been investigated in rodent models, which were particular...
The brain is one of the most complex organs, responsible for the advanced intellectual and cognitive...
Background: Brain organoids are self-organized from human pluripotent stem cells and developed into ...
Human brain development is an intricate process that involves closely timed coordination of cell pro...
The field of developmental neuroscience is benefitting from recent technological advances that allow...
The field of developmental neuroscience is benefitting from recent technological advances that allow...
The past decade has seen an explosion in the identification of genetic causes of neurodevelopmental ...
AbstractThe ability to model human brain development in vitro represents an important step in our st...
Stem cell studies are being currently widely used in neuroscience particularly for degenerative, dev...
Over the past years, brain development has been investigated in rodent models, which were particular...