Achieving high accuracy in orthology inference is essential for many comparative, evolutionary and functional genomic analyses, yet the true evolutionary history of genes is generally unknown and orthologs are used for very different applications across phyla, requiring different precision-recall trade-offs. As a result, it is difficult to assess the performance of orthology inference methods. Here, we present a community effort to establish standards and an automated web-based service to facilitate orthology benchmarking. Using this service, we characterize 15 well-established inference methods and resources on a battery of 20 different benchmarks. Standardized benchmarking provides a way for users to identify the most effective methods fo...
The identification of orthologs—genes in different species which descended from the same gene in the...
The identification of orthologs-genes pairs descended from a common ancestor through speciation, rat...
Orthobench is the standard benchmark to assess the accuracy of orthogroup inference methods. It cont...
Achieving high accuracy in orthology inference is essential for many comparative, evolutionary and f...
Achieving high accuracy in orthology inference is essential for many comparative, evolutionary and f...
The identification of evolutionarily related genes across different species—orthologs in particular—...
The Orthology Benchmark Service (https://orthology.benchmarkservice.org) is the gold standard for or...
Accurate orthology prediction is crucial for many applications in the post-genomic era. The lack of ...
The identification of orthologs-genes in different species which descended from the same gene in the...
The Orthology Benchmark Service evaluation, supported and maintained by the Quest for Orthologs cons...
Accurate orthology prediction is crucial for many applications in the post-genomic era. The lack of ...
<div><p>Accurate orthology prediction is crucial for many applications in the post-genomic era. The ...
The identification of orthologs—genes pairs descended from a common ancestor through speciation, rat...
The identification of orthologs—genes in different species which descended from the same gene in the...
The identification of orthologs-genes pairs descended from a common ancestor through speciation, rat...
Orthobench is the standard benchmark to assess the accuracy of orthogroup inference methods. It cont...
Achieving high accuracy in orthology inference is essential for many comparative, evolutionary and f...
Achieving high accuracy in orthology inference is essential for many comparative, evolutionary and f...
The identification of evolutionarily related genes across different species—orthologs in particular—...
The Orthology Benchmark Service (https://orthology.benchmarkservice.org) is the gold standard for or...
Accurate orthology prediction is crucial for many applications in the post-genomic era. The lack of ...
The identification of orthologs-genes in different species which descended from the same gene in the...
The Orthology Benchmark Service evaluation, supported and maintained by the Quest for Orthologs cons...
Accurate orthology prediction is crucial for many applications in the post-genomic era. The lack of ...
<div><p>Accurate orthology prediction is crucial for many applications in the post-genomic era. The ...
The identification of orthologs—genes pairs descended from a common ancestor through speciation, rat...
The identification of orthologs—genes in different species which descended from the same gene in the...
The identification of orthologs-genes pairs descended from a common ancestor through speciation, rat...
Orthobench is the standard benchmark to assess the accuracy of orthogroup inference methods. It cont...