Add to ORKGEarly neurovascular coupling (NVC) changes in Alzheimer's disease can potentially provide imaging biomarkers to assist with diagnosis and treatment. Previous efforts to quantify NVC with intrinsic signal imaging have required assumptions of baseline optical pathlength to calculate changes in oxy- and deoxy-hemoglobin concentrations during evoked stimuli. In this work, we present an economical spatial frequency domain imaging (SFDI) platform utilizing a commercially available LED projector, camera, and off-the-shelf optical components suitable for imaging dynamic optical properties. The fast acquisition platform described in this work is validated on silicone phantoms and demonstrated in neuroimaging of a mouse model. © 2012 SPIE
The aim of this research was to develop non-transgenic rodent models relevant to Alzheimer’s disease...
Neuroimaging techniques represent powerful tools to assess disease-specific cellular, biochemical an...
The goal of this work is to enable high-speed, video-rate (>30 Hz) spatial frequency domain imagi...
Early neurovascular coupling (NVC) changes in Alzheimer's disease can potentially provide imaging bi...
Extensive changes in neural tissue structure and function accompanying Alzheimer's disease (AD) sugg...
Abstract.There is a need for cost effective, quantitative tissue spectroscopy and imaging systems in...
Background—There currently is a need for cost-effective, quantitative techniques to evaluate the gra...
BackgroundThere currently is a need for cost-effective, quantitative techniques to evaluate the grad...
Quantifying rapidly varying perturbations in cerebral tissue absorption and scattering can potential...
The communication between neurons and blood vessels to supply cells in the brain with energy is a co...
International audienceFifty million people worldwide are affected by dementia, a heterogeneous neuro...
AbstractNeuroimaging techniques represent powerful tools to assess disease-specific cellular, bioche...
We describe a multi-angle rotational optical imaging (MAROI) system for in vivo monitoring of physio...
Fifty million people worldwide are affected by dementia, a heterogeneous neurodegenerative condition...
Spatial Frequency Domain Imaging (SFDI) is a non-contact imaging method that uses multiple frequency...
The aim of this research was to develop non-transgenic rodent models relevant to Alzheimer’s disease...
Neuroimaging techniques represent powerful tools to assess disease-specific cellular, biochemical an...
The goal of this work is to enable high-speed, video-rate (>30 Hz) spatial frequency domain imagi...
Early neurovascular coupling (NVC) changes in Alzheimer's disease can potentially provide imaging bi...
Extensive changes in neural tissue structure and function accompanying Alzheimer's disease (AD) sugg...
Abstract.There is a need for cost effective, quantitative tissue spectroscopy and imaging systems in...
Background—There currently is a need for cost-effective, quantitative techniques to evaluate the gra...
BackgroundThere currently is a need for cost-effective, quantitative techniques to evaluate the grad...
Quantifying rapidly varying perturbations in cerebral tissue absorption and scattering can potential...
The communication between neurons and blood vessels to supply cells in the brain with energy is a co...
International audienceFifty million people worldwide are affected by dementia, a heterogeneous neuro...
AbstractNeuroimaging techniques represent powerful tools to assess disease-specific cellular, bioche...
We describe a multi-angle rotational optical imaging (MAROI) system for in vivo monitoring of physio...
Fifty million people worldwide are affected by dementia, a heterogeneous neurodegenerative condition...
Spatial Frequency Domain Imaging (SFDI) is a non-contact imaging method that uses multiple frequency...
The aim of this research was to develop non-transgenic rodent models relevant to Alzheimer’s disease...
Neuroimaging techniques represent powerful tools to assess disease-specific cellular, biochemical an...
The goal of this work is to enable high-speed, video-rate (>30 Hz) spatial frequency domain imagi...