This dissertation traces three interconnected material histories embedded within German-American artist Eva Hesse's sculptural works constructed between 1964-1969. At only 34, she amassed an extensive oeuvre before an untimely death in 1970 from cancer. Most of Hesse's sculptural artworks were constructed during a residency in Kettwig an der Ruhr, West Germany, and in her New York City studio. During this time, the artist conducted pioneering experimentation with industrial and chemical materials, newly made available to the art community by commercial and manufacturing industries. Three chapters attend to the material, cultural, sociological, and geopolitical context of Hesse's artistic exploration of synthetic substances – respectively in...