IntroductionComposite scores based on psychometrically rigorous cognitive assessments are well suited for early diagnosis and disease monitoring.MethodsWe developed and cross-validated the Brain Health Assessment-Cognitive Score (BHA-CS), based on a brief computerized battery, in 451 cognitively normal (CN) and 399 cognitively impaired (mild cognitive impairment [MCI] or dementia) older adults. We investigated its long-term reliability and reliable change indices at longitudinal follow-up (N = 340), and the association with amyloid beta (Aβ) burden in the CN subgroup with Aβ positron emission tomography (N = 119).ResultsThe BHA-CS was accurate at detecting cognitive impairment and exhibited excellent long-term stability....
To date evidence of the relationship between cognition and Aβ amyloid during the early stages of Alz...
Backgroundβ-amyloid (Aβ) and tau positron emission tomography (PET) detect the pathological changes ...
Cognitively-normal people with evidence of β-amyloid (Aβ) pathology and subtle cognitive dysfunction...
Introduction: To improve the detection of changes in Alzheimer's disease (AD), we designed the cogni...
BACKGROUND: Computerized cognitive assessments may improve Alzheimer's disease (AD) secondary preven...
BackgroundComputerized cognitive assessments may improve Alzheimer's disease (AD) secondary preventi...
Introduction: We investigated whether monthly assessments of a computerized cognitive composite (C3)...
INTRODUCTION: Cognitive composite scores developed for preclinical Alzheimer's disease (AD) often co...
AbstractIntroductionCognitive composite scores developed for preclinical Alzheimer's disease (AD) of...
ImportanceAs Alzheimer disease (AD) research moves to intervene in presymptomatic phases of the dise...
Background: We sought to identify optimal approaches by calibrating longitudinal cognitive performan...
markdownabstract__Introduction__ Cognitive testing in Alzheimer's disease (AD) is essential for esta...
Background: To date evidence of the relationship between cognition and Aβ amyloid during the early s...
Background: High β-amyloid (Aβ) is associated with faster memory decline in healthy individuals and ...
Background: To date evidence of the relationship between cognition and Aβ amyloid during the early s...
To date evidence of the relationship between cognition and Aβ amyloid during the early stages of Alz...
Backgroundβ-amyloid (Aβ) and tau positron emission tomography (PET) detect the pathological changes ...
Cognitively-normal people with evidence of β-amyloid (Aβ) pathology and subtle cognitive dysfunction...
Introduction: To improve the detection of changes in Alzheimer's disease (AD), we designed the cogni...
BACKGROUND: Computerized cognitive assessments may improve Alzheimer's disease (AD) secondary preven...
BackgroundComputerized cognitive assessments may improve Alzheimer's disease (AD) secondary preventi...
Introduction: We investigated whether monthly assessments of a computerized cognitive composite (C3)...
INTRODUCTION: Cognitive composite scores developed for preclinical Alzheimer's disease (AD) often co...
AbstractIntroductionCognitive composite scores developed for preclinical Alzheimer's disease (AD) of...
ImportanceAs Alzheimer disease (AD) research moves to intervene in presymptomatic phases of the dise...
Background: We sought to identify optimal approaches by calibrating longitudinal cognitive performan...
markdownabstract__Introduction__ Cognitive testing in Alzheimer's disease (AD) is essential for esta...
Background: To date evidence of the relationship between cognition and Aβ amyloid during the early s...
Background: High β-amyloid (Aβ) is associated with faster memory decline in healthy individuals and ...
Background: To date evidence of the relationship between cognition and Aβ amyloid during the early s...
To date evidence of the relationship between cognition and Aβ amyloid during the early stages of Alz...
Backgroundβ-amyloid (Aβ) and tau positron emission tomography (PET) detect the pathological changes ...
Cognitively-normal people with evidence of β-amyloid (Aβ) pathology and subtle cognitive dysfunction...