Project 1 Analyzing Tumor Microenvironment and Exploiting its Characteristics in Search of Optimizing Cancer Therapy Including Neutron Capture Therapy (R2P1)

In case that corrections are made, an errata will be provided in the following webpage: https://www.rri.kyoto-u.ac.jp/PUB/report/PR/ProgRep2020/ProgRep2020.htmlPR1-1 Significance of combination with both continuous administration of hypoxic cytotoxin, tirapazamine and mild temperature hyperthermia in BNCT in terms of local tumor control and lung metastatic potential /S. Masunaga et al. (R2P1-1) [4]PR1-2 Development of Amino Acid Derivatives Containing ¹⁰B-Clusters for BNCT /A. Matsushita et al. (R2P1-2) [5]PR1-3 Proteolysis of a Histone Acetyl Reader Protein Induces Chemoresistance of Cancer Cells under Hypoxia by Inhibiting Cell Cycle Progression in S Phase /T. Haitani et al. (R2P1-3) [6]PR1-4 Cancer-Targeting Hyaluronic Acid/Carboranyl Pyrene Complex for Boron Neutron Capture Therapy /K. Yamana et al. (R2P1-6) [7]PR1-5 An evaluation of stratified mouse model and the response of tumor cells to BNCT /S. Imamichi et al. (R2P1-9) [8]PR1-6 Attempts to sensitize tumor cells by exploiting the tumor microenvironment /Y. Sanada et al. (R2P1-12) [9