Tuberculosis research in South Africa over the past 30 years : from bench to bedside

CITATION: Warren, R. et al. 2019. Tuberculosis research in South Africa over the past 30 years: From bench to bedside. South African Medical Journal, 109(11b):45-52. doi:10.7196/SAMJ.2019.v109i11b.14249The original publication is available at http://www.samj.org.za/index.php/samj/indexENGLISH ABSTRACT: The South African Medical Research Council Centre for Tuberculosis Research has a rich history of high-impact research that has influenced our understating of this hyper-epidemic which is further exacerbated by the emergence and spread of drug-resistant forms of the disease. This review aims to summarise the past 30 years of research conducted in the Centre which has influenced the way that tuberculosis (TB) is diagnosed and treated. The review includes the development of new technologies for rapid screening of people with probable TB and the repurposing of human diagnostics for wildlife conservation.South African Medical Research CouncilDST-NRF Centre of Excellence for Biomedical Tuberculosis ResearchNRF South African Research Chair Initiative (SARChI)http://www.samj.org.za/index.php/samj/article/view/12796Publisher’s versio