Nox2 Deficiency Reduces Cartilage Damage and Ectopic Bone Formation in an Experimental Model for Osteoarthritis

The increased synthesis of inducible nitric oxide inhibits IL-1ra synthesis by human articular chondrocytes: possible role in osteoarthritic cartilage degradation

Pelletier, Jean-Pierre
Mineau, François
Ranger, Pierre
Tardif, Ginette
Martel-Pelletier, Johanne

March 1996

SummaryThe degradation of osteoarthritic (OA) cartilage is likely related to the synthesis and the r...

Deficiency of Nrf2 accelerates the effector phase of arthritis and aggravates joint disease

Maicas, Nuria
Ferrándiz, María Luisa
Brines, Rita
Ibáñez, Lidia
Cuadrado, Antonio
Koenders, Marije I.
Van Den Berg, Wim B.
Alcaraz, María José

August 2011

This is a copy of an article published in the ANTIOXIDANTS & REDOX SIGNALING (15-08-2011) copyright ...

ORIGINAL RESEARCH COMMUNICATION Redox Regulation of Pro-IL-1b Processing May Contribute to the Increased Severity of Serum-Induced Arthritis

August 2016

Aims: To elucidate the role of reactive oxygen species (ROS) in arthritis and to identify targets of...

Osteoarthritis and nitric oxide

Abramson, Steven B.

June 2008

AbstractOsteoarthritis (OA) is caused by both biochemical and mechanical factors. While the mechanis...

IL-1beta mediates MMP secretion and IL-1beta neosynthesis via upregulation of p22phox and NOX4 activity in human articular chondrocytes

Rousset, F.
Hazane-Puch, F.
Pinosa, C.
Nguyen, Minh Vu Chong
Grange, L.
Soldini, A.
Rubens-Duval, B.
Dupuy, C.
Morel, F.
Lardy, B.

January 2015

peer reviewedObjectives: Osteoarthritis (OA) is characterized by a progressive alteration of the bio...

The role of NOX2-derived reactive oxygen species in collagenase-induced osteoarthritis

Dalen, S.C.M. van
Kruisbergen, N.N.L.
Walgreen, B.
Helsen, M.M.A.
Sloetjes, A.W.
Cremers, N.A.J.
Koenders, M.I.
Loo, F.A.J. van de
Blom, A.B.
Kraan, P.M. van der
Lent, P.L.E.M. van
Bosch, M.H.J. van den

January 2018

Contains fulltext : 198495.pdf (publisher's version ) (Closed access

Stimulation of cyclooxygenase-2-activity by nitric oxide-derived species in rat chondrocyte: lack of contribution to loss of cartilage anabolism1

Nédélec, Emmanuelle
Abid, Amr
Cipolletta, Christine
Presle, Nathalie
Terlain, Bernard
Netter, Patrick
Jouzeau, Jean-Yves

April 2001

Footnote 1:Abbreviations: ACT D, actinomycine D; CHX, cycloheximide; COX, cyclooxygenase; CuDips, Cu...

Selective inhibition of inducible nitric oxide synthase prevents lipid peroxidation in cartilage from patients with osteoarthritis

Bentz, Mireille

April 2015

INTRODUCTION: Emerging evidence indicates that nitric oxide (NO), which is increased in osteoarthrit...

Oxidative stress and chronic inflammation in osteoarthritis:can Nrf2 counteract these partners in crime?

Marchev, Andrey S.
Dimitrova, Petya A.
Burns, Andrew J.
Kostov, Rumen
Dinkova-Kostova, Albena
Georgiev, Milen I.

September 2017

Osteoarthritis (OA) is an age-related joint degenerative disease associated with pain, joint deformi...

Osteoarthritis-Related Inflammation Blocks TGF-beta's Protective Effect on Chondrocyte Hypertrophy via (de)Phosphorylation of the SMAD2/3 Linker Region

Thielen, N.G.M.
Neefjes, M.
Wiegertjes, R.
Akker, Guus van den
Vitters, E.L.
Beuningen, H.M. van
Blaney Davidson, E.N.
Koenders, M.I.
Lent, P.L.E.M. van
Loo, F.A.J. van de
Caam, A.P.M. van
Kraan, P.M. van der

January 2021

Contains fulltext : 236920.pdf (Publisher’s version ) (Open Access

Regulation of the nitric oxide production resulting from the glucocorticoid-insensitive expression of iNOS in human osteoarthritic cartilage

Vuolteenaho, K.
Moilanen, T.
Al-Saffar, N.
Knowles, R.G.
Moilanen, E.

October 2001

AbstractObjective Nitric oxide (NO) produced by cartilage and synovial membranes is implicated in th...

Connection between Osteoarthritis and Nitric Oxide: From Pathophysiology to Therapeutic Target

Huanyu Jiang
Piyao Ji
Xiaobin Shang
Yan Zhou

February 2023

Osteoarthritis (OA), a disabling joint inflammatory disease, is characterized by the progressive des...

IL-1beta mediates MMP secretion and IL-1beta neosynthesis via upregulation of p22phox and NOX4 activity in human articular chondrocytes

Rousset, F.
Hazane-Puch, F.
Pinosa, C.
Nguyen, M.V.C.
Grange, L.
Soldini, A.
Rubens-Duval, B.
Dupuy, C.
Morel, F.
Lardy, B.

November 2015

SummaryObjectivesOsteoarthritis (OA) is characterized by a progressive alteration of the biochemical...

Evaluation d'outils pour l'étude de l'arthrose à l'échelle protéique, cellulaire et animale

Drevet, Sabine

May 2020

Osteoarthritis (OA) is a chronic degenerative disease affecting millions of people around the world ...

Development of a simple osteoarthritis model useful to predict in vitro the anti-hypertrophic action of drugs

Allas, Lyess
Rochoux, Quitterie
Leclercq, Sylvain
Boumediene, Karim
Baugé, Catherine

January 2019

International audienceOsteoarthritis (OA) is characterized by cartilage degradation, inflammation, a...

The increased synthesis of inducible nitric oxide inhibits IL-1ra synthesis by human articular chondrocytes: possible role in osteoarthritic cartilage degradation

Pelletier, Jean-Pierre
Mineau, François
Ranger, Pierre
Tardif, Ginette
Martel-Pelletier, Johanne

March 1996

SummaryThe degradation of osteoarthritic (OA) cartilage is likely related to the synthesis and the r...

Deficiency of Nrf2 accelerates the effector phase of arthritis and aggravates joint disease

Maicas, Nuria
Ferrándiz, María Luisa
Brines, Rita
Ibáñez, Lidia
Cuadrado, Antonio
Koenders, Marije I.
Van Den Berg, Wim B.
Alcaraz, María José

August 2011

This is a copy of an article published in the ANTIOXIDANTS & REDOX SIGNALING (15-08-2011) copyright ...

ORIGINAL RESEARCH COMMUNICATION Redox Regulation of Pro-IL-1b Processing May Contribute to the Increased Severity of Serum-Induced Arthritis

August 2016

Aims: To elucidate the role of reactive oxygen species (ROS) in arthritis and to identify targets of...

Osteoarthritis and nitric oxide

Abramson, Steven B.

June 2008

AbstractOsteoarthritis (OA) is caused by both biochemical and mechanical factors. While the mechanis...

IL-1beta mediates MMP secretion and IL-1beta neosynthesis via upregulation of p22phox and NOX4 activity in human articular chondrocytes

Rousset, F.
Hazane-Puch, F.
Pinosa, C.
Nguyen, Minh Vu Chong
Grange, L.
Soldini, A.
Rubens-Duval, B.
Dupuy, C.
Morel, F.
Lardy, B.

January 2015

peer reviewedObjectives: Osteoarthritis (OA) is characterized by a progressive alteration of the bio...

The role of NOX2-derived reactive oxygen species in collagenase-induced osteoarthritis

Dalen, S.C.M. van
Kruisbergen, N.N.L.
Walgreen, B.
Helsen, M.M.A.
Sloetjes, A.W.
Cremers, N.A.J.
Koenders, M.I.
Loo, F.A.J. van de
Blom, A.B.
Kraan, P.M. van der
Lent, P.L.E.M. van
Bosch, M.H.J. van den

January 2018

Contains fulltext : 198495.pdf (publisher's version ) (Closed access

Stimulation of cyclooxygenase-2-activity by nitric oxide-derived species in rat chondrocyte: lack of contribution to loss of cartilage anabolism1

Nédélec, Emmanuelle
Abid, Amr
Cipolletta, Christine
Presle, Nathalie
Terlain, Bernard
Netter, Patrick
Jouzeau, Jean-Yves

April 2001

Footnote 1:Abbreviations: ACT D, actinomycine D; CHX, cycloheximide; COX, cyclooxygenase; CuDips, Cu...

Selective inhibition of inducible nitric oxide synthase prevents lipid peroxidation in cartilage from patients with osteoarthritis

Bentz, Mireille

April 2015

INTRODUCTION: Emerging evidence indicates that nitric oxide (NO), which is increased in osteoarthrit...

Oxidative stress and chronic inflammation in osteoarthritis:can Nrf2 counteract these partners in crime?

Marchev, Andrey S.
Dimitrova, Petya A.
Burns, Andrew J.
Kostov, Rumen
Dinkova-Kostova, Albena
Georgiev, Milen I.

September 2017

Osteoarthritis (OA) is an age-related joint degenerative disease associated with pain, joint deformi...

Osteoarthritis-Related Inflammation Blocks TGF-beta's Protective Effect on Chondrocyte Hypertrophy via (de)Phosphorylation of the SMAD2/3 Linker Region

Thielen, N.G.M.
Neefjes, M.
Wiegertjes, R.
Akker, Guus van den
Vitters, E.L.
Beuningen, H.M. van
Blaney Davidson, E.N.
Koenders, M.I.
Lent, P.L.E.M. van
Loo, F.A.J. van de
Caam, A.P.M. van
Kraan, P.M. van der

January 2021

Contains fulltext : 236920.pdf (Publisher’s version ) (Open Access

Regulation of the nitric oxide production resulting from the glucocorticoid-insensitive expression of iNOS in human osteoarthritic cartilage

Vuolteenaho, K.
Moilanen, T.
Al-Saffar, N.
Knowles, R.G.
Moilanen, E.

October 2001

AbstractObjective Nitric oxide (NO) produced by cartilage and synovial membranes is implicated in th...

Connection between Osteoarthritis and Nitric Oxide: From Pathophysiology to Therapeutic Target

Huanyu Jiang
Piyao Ji
Xiaobin Shang
Yan Zhou

February 2023

Osteoarthritis (OA), a disabling joint inflammatory disease, is characterized by the progressive des...

IL-1beta mediates MMP secretion and IL-1beta neosynthesis via upregulation of p22phox and NOX4 activity in human articular chondrocytes

Rousset, F.
Hazane-Puch, F.
Pinosa, C.
Nguyen, M.V.C.
Grange, L.
Soldini, A.
Rubens-Duval, B.
Dupuy, C.
Morel, F.
Lardy, B.

November 2015

SummaryObjectivesOsteoarthritis (OA) is characterized by a progressive alteration of the biochemical...

Evaluation d'outils pour l'étude de l'arthrose à l'échelle protéique, cellulaire et animale

Drevet, Sabine

May 2020

Osteoarthritis (OA) is a chronic degenerative disease affecting millions of people around the world ...

Development of a simple osteoarthritis model useful to predict in vitro the anti-hypertrophic action of drugs

Allas, Lyess
Rochoux, Quitterie
Leclercq, Sylvain
Boumediene, Karim
Baugé, Catherine

January 2019

International audienceOsteoarthritis (OA) is characterized by cartilage degradation, inflammation, a...

The increased synthesis of inducible nitric oxide inhibits IL-1ra synthesis by human articular chondrocytes: possible role in osteoarthritic cartilage degradation

Pelletier, Jean-Pierre
Mineau, François
Ranger, Pierre
Tardif, Ginette
Martel-Pelletier, Johanne

March 1996

SummaryThe degradation of osteoarthritic (OA) cartilage is likely related to the synthesis and the r...

Deficiency of Nrf2 accelerates the effector phase of arthritis and aggravates joint disease

Maicas, Nuria
Ferrándiz, María Luisa
Brines, Rita
Ibáñez, Lidia
Cuadrado, Antonio
Koenders, Marije I.
Van Den Berg, Wim B.
Alcaraz, María José

August 2011

This is a copy of an article published in the ANTIOXIDANTS & REDOX SIGNALING (15-08-2011) copyright ...

ORIGINAL RESEARCH COMMUNICATION Redox Regulation of Pro-IL-1b Processing May Contribute to the Increased Severity of Serum-Induced Arthritis

August 2016

Aims: To elucidate the role of reactive oxygen species (ROS) in arthritis and to identify targets of...

Nox2 Deficiency Reduces Cartilage Damage and Ectopic Bone Formation in an Experimental Model for Osteoarthritis

Abstract

Extracted data

Nox2 Deficiency Reduces Cartilage Damage and Ectopic Bone Formation in an Experimental Model for Osteoarthritis

Abstract

Extracted data

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