Prognostic value of clinical scoring systems and coagulation parameters in severe community aquired pneumonia

Introduction Predicting ICU outcome in community-acquired pneumonia (CAP) is important for effective clinical decision making. CAP is associated with coagulation abnormalities even in patients with nonsevere illness, and these parameters may improve the ability of simple clinical scores to expect mortality in severe CAP. Patients and methods A prospective study was conducted on 100 patients with a primary diagnosis of CAP and who needed admission to ICU Minia University Hospital between the period of September 2018 and October 2019. The study aimed to evaluate the value of clinical scoring systems and coagulation parameters to predict prognosis of severe CAP. Results The overall ICU mortality was 41%. Following multivariable regression, male sex, Simplified Acute Physiological Score II score, diagnosis of cancer, and prothrombin time (PT) were significantly associated with ICU mortality. Apart from Acute Physiologic Assessment and Chronic Health Evaluation III score, all other severity scores, including the CURB-65 score, can differentiate between ICU survivors and nonsurvivors when calculated at the time of admission to ICU (P