Effects of Citrus aurantifolia peel essential oil on serum cholesterol levels in Wistar rats

The present study seeks to evaluate the effects of Citrus aurantifolia peel essential oil on serum triglyceride and cholesterols in Wistar rats. Thirty Wistar rats were divided into 5 groups: control, sham, and 3 experimental groups. The animals were treated in 2 phases: first, except for control group, which received normal saline, the rest of the groups were fed with a high cholesterol regimen to induce hyperlipidemia; then, the 3 experimental groups were treated with Citrus aurantifolia peel essential oil in 3 different doses: 25, 50, and 100 m lit/kg. Results: The sham group demonstrated a significant rise in mean serum triglyceride, cholesterol, and LDL level in comparison with the control group (