The article offers a general vision of the ancient and modern reception of the pagan philosopher Hypatia whose martyrdom in 415 symbolizes the religious obscurantism of the early Christians. It analyzes the mechanisms in the ancient transmission of knowledge, which have underwritten a long tradition in the European history of ideas. Specifically, it questions the tradition that emerged from texts that spoke about Hypatia: for example, the letters Synesius of Cyrene supposedly sent to the woman he designates as his Mistress. Far from revealing the historic reality of a very platonic love between a scholar and a woman whose intelligence was seen as quasi-divine, these letters reveal instead a fictive philosophical couple, where the chosen one...