Biochemical studies of Raktapittantaka Louha

Aims: The aim of this study is to investigate the toxicological and pharmacological aspects of the popular ayurvedic preparation Raktapittantaka Louha (RPT) which has been used for hyperacidity non ulcer dyspepsia and haemorhagic diseases. Methods: Raktapittantaka Louha was administered orally to male albino rat. After 46 days of treatment period animals were fasted for 18 hours after the last administration. Biochemical studies including; total protein, serum albumin, blood urea nitrogen, bilirubin, creatinine, aspartate aminotransferase, alanine aminotransferase & alkaline phosphatase were conducted. Results: Triglyceride level was significantly (p=0.001) lowered in the RPT group than the corresponding control group. Total cholesterols, LDL, VLDL and HDL levels were raised significantly (p=0.05) in the RPT group. The amount of Albumin, Creatinine and Urea in serum were significantly (p=0.05) increased in RPT group. Lowering of Triglyceride is particularly beneficial in the condition where triglyceride is a burden. Further studies are needed to be conducted to reach a concrete decision about its application in human