Inflammation precedes sodium retention in raised blood pressure in young adults

Introduction: The pathogenesis of essential hypertension remains elusive. It is argued that that it could be a systemic, low-grade inflammatory disease, or renal angiotensin aldosterone system dysregulation leading to sodium retention. Most studies were conducted among the general population but data among young adults are lacking. This study aims to compare the inflammatory parameters and sodium in young adults with different blood pressure statuses. Methods and materials: We conducted analyses in healthy 240 individuals aged 18-45 years that had been included in young adults with essential hypertension study in Pahang between April to December 2017. We categorized them into normotension (